Thrilled to finally announce our work on the selectivity of disordered protein condensation in Nature Chemistry. Great collaboration with Jeetain Mittal Led by Rachel Welles and Kandarp Sojitra. rdcu.be/dxP4r. See related work by Brangwynne lab rdcu.be/dzddw

Online Now: The proteomic landscape of genotoxic stress-induced micronuclei dlvr.it/T3N99F

A new #SciencePerspective by Ziyad Al-Aly, MD and Eric Topol identifies key issues that need to be prioritized in the study of #LongCovid. Learn more: scim.ag/62B

SARS-CoV-2 targets ribosomal RNA biogenesis dlvr.it/T3cDKy

New faculty position opening: Assistant Professor - Pathobiology of Disease jobs.utoronto.ca/job/Toronto-As…

New paper from the lab! Led by Tajinder Ubhi, we used CRISPR-Cas chemical genetic screens to identify vulnerabilities in pancreatic cancer. And found… APOBEC3-family cytidine deaminases! Online now Nature Cancer nature.com/articles/s4301…

Congrats 👏 Talya and I very much look forward to seeing you take this to the next level in your own group soon!

Our new paper about the structural mechanism by which RAD51 assembles at double-stranded DNA break sites on chromatin has been published in Nature! doi.org/10.1038/s41586… #CryoEM #Nucleosome #RAD51 #DNArepair

Researchers argue that long #genes age faster -- and this quirk may play a role in how people age. Read more from this Opinion in Trends in Genetics: cell.com/trends/genetic… Tecnun Ander Izeta, MolecularGenetics@ErasmusMC Jan H.J. Hoeijmakers, Northwestern Feinberg School of Medicine Thomas Stoeger

New durocher lab paper! Final version of Tiffany Cho's work on charting the genetic architecture of SUMO E1 inhibition and characterization of NFATC2IP is now published (open access) 1/5 genesdev.cshlp.org/cgi/content/lo…

Lab paper is out! Ke Cong and Nate MacGilvary in collaboration with Tovah Day lab, FANCJ-G4 biology reveals PARP1 activity, not trapping, causes toxicity in BRCA1 deficient cells, rdcu.be/dCcAU

1/ We are excited to release our new preprint: "Rules of engagement for condensins and cohesins guide mitotic chromosome formation" biorxiv.org/content/10.110…

A post-doctoral researcher from @UofTMedicine, recently showed how SARS-CoV-2 disrupts the manufacture of proteins. #UofT utoronto.ca/news/covid-19-…

⚡️🔬📣 Excited to share our new nature article building and evaluating PathChat, a multimodal generative AI copilot and chatbot for human pathology. Article: nature.com/articles/s4158… Open Access Link: rdcu.be/dKC0r We leverage our previous success in building

Just out in Cell Reports! Dream team of former MD/PhD student Jess Williams, res. scientist Ivan Surovtsev, collaborator Kaushik Ragunathan Kaushik Ragunathan + many awesome contributors discovered that Swi6/HP1a condensates are key to nuclear mechanics. tinyurl.com/2r4jkamf 1/n

Super excited to share that our paper is online now!🎊🥂 We uncover the fundamental mechanism of how BLM helicase deficiency drives rDNA instabily and compromises global genome integrity - a significant insight into the molecular basis of Bloom Syndrome. nature.com/articles/s4146…