PARP Inhibitors for Breast Cancer Treatment JAMA Oncology jamanetwork.com/journals/jamao…

In a major blow to public health, today the The White House issued a shocking announcement that it is indefinitely delaying the finalization of the U.S. FDA’s rule to eliminate the sale of menthol cigarettes, with no mention of flavored cigars. #ProhibitMenthol fightcancer.org/releases/admin…

For mCRPC patients previously treated with ADT+ARPI, the main treatment recommendation is docetaxel, regardless of DDR alterations.

#APCCC24 Advanced Prostate Cancer Consensus Conference silke gillessen aurelius omlin OncoAlert Daniel Castellano Elena Castro Simon C Stacy Loeb, MD Nick James Christopher Sweeney, MBBS…

NEW FINDINGS: Diversity in #ClinicalTrials is critical for understanding how well a treatment may work in different populations. A new study done by CCR researchers describes representation based on sex, age and ethnicity in clinical trials done at CCR.

National Cancer Institute, NIH Intramural

As promised...

#InPress

It’s #DNADay 2024 , in other words, time for my annual “Dr. Rosalind Franklin should loom large in this picture” tweet.
#DNADay #DNADay 24 🧬

Many are performing imaging earlier with rising PSA post radical RT.
Daniel E Spratt argues: 'what's the point?' ... creates confusion, no evidence for local salvage therapy.
Advanced Prostate Cancer Consensus Conference #APCCC24 #PSMA

At the age of 23, before she’d even earned her PhD, Carol Greider made the discovery that would earn her the 2009 medicine prize. Along with her supervisor and co-laureate Elizabeth Blackburn she discovered the enzyme telomerase.

New evidence-based PCF Prostate Cancer Screening Guidelines for Black Men in the U.S. recommend that Black men consider PSA screening between ages 40-45, and screen annually depending on PSA levels and health status. 🧵⬇️

Final FY24 budget for US research is a disaster.
Budgets of federal agencies are mostly or cut down

NIH $47.08B flat
NSF $9.06B (-5%)
NASA Sci. $7.33B (-6%)
CDC $9.2B flat
DOE Sci. $8.24B (+1.7%)
ARPA-E 0.46B (-2%)
DOD Sci. $2.6B (-9%)
DARPA $4.1B flat
Global Health $10B (-5%)

Happy Monday 💐

Nucleolar stress caused by arginine-rich peptides triggers a ribosomopathy and accelerates aging in mice dlvr.it/T5mjw6

Call to action: To address Black cancer disparities, focus on research prioritization and clinical studies inclusion. Guest editorial by Kimlin Tam Ashing, Nadine J. Barrett, PhD, MA., MS, Kim F. Rhoads, Folakemi T. Odedina, Dr. Hayley S. Thompson, and camille ragin.
cancerletter.com/guest-editoria…

Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape dlvr.it/T5lQZh

Congratulations Dr. Hussain Hafiz Muhammad Jafar Hussain of Dr. Rui Chen's lab on your career-starter award from the Knights Templar Eye Foundation!

Congratulations to Dr. Fady Joudah for winning the 2024 Jackson Poetry Prize! Your talent and courage to speak amidst the unspeakable have earned you this well-deserved recognition. Here's to celebrating your achievement and the impact of your poetry on the world. 🎉📜 #BCMDoM

.MD Anderson Cancer Center researchers describe novel molecular underpinnings 📌 and metabolic drivers of ferroptosis and highlight #ProstateCancer -specific susceptibilities to #ferroptosis . Daniel E. Frigo, Ph.D.

✅ Check out their perspective in Nature Reviews Urology!
go.nature.com/49G6MSg

College admission essay content has a stronger correlation with household income (R2 = 16%) than SAT scores.
This explains how removing standardized tests can increase inequality.
Based on 240,000 admission essays to the University of California. science.org/doi/full/10.11…