Excited to share our latest review led by AliceAmitrano & Debanik Choudhury, PhD! We dive into the mechanisms of confined cell migration, exploring how ion channels, cell cytoskeleton, and fluidic & solid cues drive motility & metabolic reprogramming. Read more: doi.org/10.1016/j.ceb.…

Happy to share our latest research article, "The activation of INF2 by Piezo1/Ca2+ is required for mesenchymal-to-amoeboid transition in confined environments," in Current Biology: authors.elsevier.com/a/1koXe3QW8SA2… Graphical abstract:

Huge congrats to my first-year PhD student, Josiah Power Josiah Power on receiving an U.S. National Science Foundation GRFP! At just 19 and with a double-major in ChemBE & Biochem, he took 5 doctoral-level courses last fall (vs. the usual 3) and aced them all. Incredible talent and drive- well deserved!

Three weeks left until the abstract submission deadline for our joint MBI-MPI #mechanobiology conference this September! Mechanobiology Institute Max Planck Society To early career scientists- be sure to apply for a travel award to present your work! mbi.nus.edu.sg/events/mbiconf…

How do altered levels of lamins and other nuclear envelope proteins contribute to cancer metastasis, and how does this relate to #mechanobiology? Learn more in our recent review by Sarah Henretta now out in npj Journals - biological physics and mechanics (doi.org/10.1038/s44341…).

Immense congrats to my amazing postdoc Debanik Choudhury, PhD for winning the Best Poster Award at the 18th Nano-Bio Symposium at The Johns Hopkins Institute for NanoBioTechnology ! In just one year, he’s co-led a COCB article doi.org/10.1016/j.ceb.……, a book chapter , and has several more in the pipeline. Well-deserved!

I'm pleased to announce that CMBE now has an impact factor of 5.0! And don't forget, there is no publishing fee.

🎉After years in the making… our work, Konstantopoulos Lab Avery, Dr Wisniewski & Dr Kalab, is out in Nature Materials! Anillin & Ect2, best known for their roles in cell division, are repurposed by cancer cells to drive confined migration and extravasation. nature.com/articles/s4156…

Pleased to share our latest collaborative work with the Devreotes Lab - Johns Hopkins University in PNASNews. Using optogenetics, we show that both insufficient and excessive Ras activity impair cell motility, underscoring the need for optimal Ras signaling and cortical tension. doi.org/10.1073/pnas.2…