Journal of Experimental & Clinical Cancer Research
@JournalofExper1
Official journal of "Regina Elena" National Cancer Institute
https://t.co/hL7ytcADtP
ID:1218124828454113283
https://go.sn.pub/jcjmdK 17-01-2020 10:56:34
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Inhibition of #autophagy -related protein 7 enhances anti-tumor #immuneresponse and improves efficacy of #immunecheckpointblockade in microsatellite instability #colorectalcancer
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jeccr.biomedcentral.com/articles/10.11โฆ
#Cholesterol
#Microsatelliteinstability
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METTL3 recruiting M2-type immunosuppressed macrophages by targeting #m6A -SNAIL-CXCL2 axis to promote #colorectalcancer pulmonary metastasis
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jeccr.biomedcentral.com/articles/10.11โฆ
#Macrophages
#Epithelialmesenchymaltransition
#RNAmodification
Using different in vitro NSCLC models, researchers showed that NSCLC cells with low #HERC5 expression had increased malignant and invasive properties.
The Journal of Experimental & Clinical Cancer Research study comes from the University Medical Center Hamburg-Eppendorf's Wikman Lab: bit.ly/43YWyet
New study!
HERC5 downregulation in #nonsmallcelllungcancer is associated with altered energy #metabolism and #metastasis
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jeccr.biomedcentral.com/articles/10.11โฆ
#Mitochondria
#Warburgeffect
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Blood-based biomarkers in patients with #nonsmallcelllungcancer treated with #immunecheckpointblockade
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jeccr.biomedcentral.com/articles/10.11โฆ
#Liquidbiopsy
#Immunotherapy
New!๐ฅ
The localization, origin, and impact of #platelets in the #tumormicroenvironment are tumor type-dependent
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jeccr.biomedcentral.com/articles/10.11โฆ
#Vascularintegrity
#Thrombocytopenia
Just published!๐พ
A paclitaxel-hyaluronan conjugate (ONCOFID-P-Bโข) in patients with BCG-unresponsive carcinoma in situ of the bladder: a dynamic assessment of the #tumormicroenvironment
Open access๐
jeccr.biomedcentral.com/articles/10.11โฆ
#Bladdercancer
#Macrophages
#Hyaluronicacid
New!๐ธ
๐๐๐๐๐ ๐ฎ๐ฉ๐ซ๐๐ ๐ฎ๐ฅ๐๐ญ๐ข๐จ๐ง ๐ข๐ง๐๐ฎ๐๐๐ฌ #๐ข๐ฆ๐ฆ๐ฎ๐ง๐๐๐ฏ๐๐ฌ๐ข๐จ๐ง ๐ฏ๐ข๐ ๐๐๐๐๐๐/๐๐๐๐ ๐๐ฑ๐ข๐ฌ ๐ข๐ง #๐ ๐๐ฌ๐ญ๐ซ๐ข๐๐๐๐ง๐๐๐ซ
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jeccr.biomedcentral.com/articles/10.11โฆ
#Immunotherapy
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Essential role of PLD2 in #hypoxia -induced #stemness and therapy resistance in #ovariantumors
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jeccr.biomedcentral.com/articles/10.11โฆ
#PhospholipaseD
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TRF2 as novel marker of tumor response to #taxane -based therapy: from mechanistic insight to clinical implication
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jeccr.biomedcentral.com/articles/10.11โฆ
#BreastCancer
#TelomericBindingFactor
#Autophagy
#DrugSensitivity
New Review!๐ฏ
๐ #๐ ๐ฅ๐ฎ๐ญ๐๐ฆ๐ข๐ง๐ tug-of-war ๐๐๐ญ๐ฐ๐๐๐ง ๐๐๐ง๐๐๐ซ and ๐ข๐ฆ๐ฆ๐ฎ๐ง๐ ๐๐๐ฅ๐ฅ๐ฌ: ๐ซ๐๐๐๐ง๐ญ ๐๐๐ฏ๐๐ง๐๐๐ฌ ๐ข๐ง ๐ฎ๐ง๐ซ๐๐ฏ๐๐ฅ๐ข๐ง๐ ๐ญ๐ก๐ ๐จ๐ง๐ ๐จ๐ข๐ง๐ ๐๐๐ญ๐ญ๐ฅ๐
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jeccr.biomedcentral.com/articles/10.11โฆ
#Metabolism
#ImmuneCells
#TumorMicroenvironment
Featured Review๐
๐๐๐ ๐ฎ๐ฅ๐๐ญ๐จ๐ซ๐ฒ ๐ฆ๐๐๐ก๐๐ง๐ข๐ฌ๐ฆ๐ฌ ๐จ๐ ๐ข๐ฆ๐ฆ๐ฎ๐ง๐ ๐๐ก๐๐๐ค๐ฉ๐จ๐ข๐ง๐ญ๐ฌ ๐๐-๐๐ ๐๐ง๐ #๐๐๐๐ -๐ ๐ข๐ง ๐๐๐ง๐๐๐ซ
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jeccr.biomedcentral.com/articles/10.11โฆ
#CancerImmunotherapy
#PDL1
#DrugIntervention
New!๐
Validation of a multiomic model of #plasmaextracellularvesicle PD-L1 and radiomics for prediction of response to #immunotherapy in NSCLC
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jeccr.biomedcentral.com/articles/10.11โฆ
#LungCancer
#Immunecheckpointinhibitor
#LiquidBiopsy
Christian Rolfo
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#๐๐๐ฌ๐จ๐ญ๐ก๐๐ฅ๐ข๐ง ๐ฉ๐ซ๐จ๐ฆ๐จ๐ญ๐๐ฌ #๐๐ซ๐๐ข๐ง๐ฆ๐๐ญ๐๐ฌ๐ญ๐๐ฌ๐ข๐ฌ ๐จ๐ #๐ง๐จ๐ง๐ฌ๐ฆ๐๐ฅ๐ฅ๐๐๐ฅ๐ฅ๐ฅ๐ฎ๐ง๐ ๐๐๐ง๐๐๐ซ ๐๐ฒ ๐๐๐ญ๐ข๐ฏ๐๐ญ๐ข๐ง๐ ๐๐๐
Full textโคต๏ธ
jeccr.biomedcentral.com/articles/10.11โฆ
#Bloodbrainbarrier
New!๐
A phase I open-label, dose-escalation study of NUC-3373, a targeted thymidylate synthase inhibitor, in patients with advanced cancer (NuTide:301)
Open access๐
jeccr.biomedcentral.com/articles/10.11โฆ
#Fluorouracil
#clinicaltrials
#Cancertherapy
#SolidTumor
Enjoy JECCR publication!๐ท
#Transcriptionalregulation of #cancerstemcell : regulatory factors elucidation and cancer treatment strategies
See here๐
jeccr.biomedcentral.com/articles/10.11โฆ
#Signalingpathway
#Epigenetics
Just Published!๐ธ
Tumor suppressor role of the complement inhibitor CSMD1 and its role in TNF-induced #neuroinflammation in #gliomas
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jeccr.biomedcentral.com/articles/10.11โฆ
#Tumornecrosisfactor
#Inflammation
#BrainTumor
New study!๐น
A high-content screen of FDA approved drugs to enhance #CART cell function: ingenol-3-angelate improves B7-H3-CAR T cell activity by upregulating B7-H3 on the target cell surface via PKCฮฑ activation
For freeโคต๏ธ
jeccr.biomedcentral.com/articles/10.11โฆ
#Tcell
#Osteosarcoma