In vitro-in vivo discordance in β-lactams activities against MBL producing Enterobacterales has been described
🔥Deciphering the Efficacy of β-Lactams in the Face of MBL Derived Resistance in Enterobacterales
Supraphysiologic Zinc in Broth is the Culprit🔥 academic.oup.com/ofid/article/d…

Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 This has bothered me for a while ... if we have been getting susceptibility testing wrong for MBLs all this time - then requires a major re-think.

Patrick Harris Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 Potentially true for many bugs-drugs-media, right? GAS & TMP-SMX, Gram negs & azithromycin.