2/2 nature.com/articles/s4146… creates a range of models whose apical and basal synapses sample from different orientation preference distributions. Compares models to their micro-dissection results –suggests that basal dendrites learn somewhat independently (dendritic spikes).

To my fans who are struggling… Try and do something positive for yourself each day and if you can, reach out to someone in worse shape. I’ve been dealing with chronic pain the past few years after multiple surgeries. For me, life can be hellish with bouts of euphoria. ❤️🙏☮️

Have you listened to Human Centered yet? Check it out here: human-centered.simplecast.com/episodes/denne… This came out well.

Honest question: How can one be a neuroscientist while simultaneously believing that mind uploading is impossible in principle? To me this is like a biologist rejecting evolution despite overwhelming evidence. Mind as neuronal computation can’t be proven but neither can evolution

Some years back at lunch at the Chateau Marmont in Hollywood with my pal, the legendary Malcolm McDowell and his friends, he grabbed my phone and tried as usual to mock me, this time by reading some review of a standup gig of mine.

December’89 was surreal for me. I bet there were 1000’s of sets before I hit that stage.

Hoping 2022 will be year more neuroscientists start taking implications of neuroscience seriously –that consciousness and self are solely product of neuronal computation. Hoping we can begin to discuss far future implications without fear of giggles from the superstitious masses.

Love Curb Your Enthusiasm but this will always be my favorite Larry David on camera moment

Richard Lewis on Buster Keaton youtu.be/UxQhaDQ19NA via YouTube There’s so much chaos, it’s time for a Buster Break. Guillermo del Toro Jimmy Kimmel @RedHourBen

R.I.P. buddy. Life can turn to shit in one moment. My heart aches for his whole family.In often a ruthless business he was historically not just hilarious but more importantly one of the kindest human beings I ever met in my career. images.app.goo.gl/cV1uNoWndx4uXZ…

Lila kept me company while I once again was mesmerized watching the Coppola masterpiece, The Conversation and the startling craft of Gene Hackman.

Introducing #panExM-t: a protocol where 🧠 tissue is expanded ✨24x✨, pan-stained with NHS ester, and immunolabeled. Now you can see everything in the brain, even synaptic densities 👇. High potential for #connectomics! bioRxiv: biorxiv.org/content/10.110…

I’m so sad today. I lost a friend who had a profound impact on my life. His aura of love and creativity will always reside within me. Rip Bob. variety.com/2022/music/new…

Despite right-wing extremist nationalism taking root in America, I cannot believe what I’m reading in this post from a Republican Party unit. What a sickening and dangerous stain on our country.

If Marjorie Taylor Greene wants to complain about student loan forgiveness, she should pay back the $180k PPP loan she had forgiven.

GOP members of Congress whose PPP loans were forgiven:

My 55 yo friend who is having postmenopausal bleeding just called me from CVS in TX bc they refused to fill her Rx for misoprostol (used to open the cervix) bc she couldn’t prove she wasn’t having an abortion. She is having surgery in 2 days. This is what total abortion bans do.

California water usage: human beings: 10% of total usage, charged at 10 cents per cubic foot agricultural usage: 40% of water usage, charged at 0.5 cents per cubic foot someone who is good at conservation please help me budget this. my state is in severe drought.

A Trump supporter who was interviewed for an HBO documentary and said that liberal politicians and celebrities are pedophiles was exposed as an actual pedophile on camera. deadstate.org/qanon-decoder-…

Far right, Trump Loving, Covid denying, anti vaxxer, 'Proud Boy' leading member, Aaron Laigaie, has reportedly died from Covid: