1/ A new paper from PhD student Marius Hedtfeld tests in vitro phase separation assays as predictors of localisation in cell compartments.

authors.elsevier.com/sd/article/S10…

We explain why homotypic or simple heterotypic LLPS assay are unlikely to predict macromolecular localization...

We'd love more ideas for improvement - we added search by ortholog IDs based on a PhD student's suggestion at the BSP.

We've just updated browse.LeishGEM.org, giving it a huge facelift and many small and big usability improvements! You can now search for ortholog gene names from select Leishmania and Trypanosoma species!

It’s been an absolute pleasure to host Marcus D Wilson in York and hear about his fascinating work on trypanosome chromatin. Interesting to think about their unusual nucleosomes and the implications for cell biology.

What a treat to have Marcus guiding us through his beautiful cryoEM data and the structural and biochemical differences between trypanosome vs mammalian nucleosomes!

Postdoctoral researchers interested in infectious diseases, nuclear organisation & gene expression - please get in touch if you would like to be hosted in my lab! Happy to have a chat!

Soil-transmitted parasitic worms infect 1.5 billion people globally, contributing to the cycle of poverty 🌍

Read more about how our researchers, as part of the STOP2030, are tackling this using #genomics 🧬

#GlobalHealth #STOP2030 #beatNTDs
sangerinstitute.blog/2024/04/11/unr…

Very grateful to receive funding by European Research Council (ERC) to study immune evasion strategies in malaria parasites. We will be looking for a parasitologist, an immunologist and a computational biologist to join us in the coming months. #ERCAdG MIVEGEC Université de Montpellier CNRS 🌍 IRD.fr

CsLinker: an algal pyrenoid assembly protein that binds the RbcL, complements across 800 My of evolution and phase separates plant Rubisco. Very excited to share this work by James Barrett, Jamie Blaza, Michael Plevin, Mark Leake, McCormick Lab. Martin Jonikas doi.org/10.1101/2024.0…

We've opened the call for our The British Academy The Leverhulme Trust
small grants scheme offering £10k. We receive so many good applications so awards will be allocated randomly between those applications that meet our quality threshold. Spread the word!
thebritishacademy.ac.uk/funding/ba-lev…

A master 2 project is available for next year (January 2025) to investigate how #trypanosomes select #microtubules for #intraflagellar transport, in collaboration with MALLET UBI Core Facility
research.pasteur.fr/en/job/protein…
master2bdc.ijm.fr/stages-bdc/

Interested in the function of the anaerobic human skin microbiome in BO production and skin health? New PhD project with me, Tony Wilkinson and Alan Cartmell in Biology at York YSBL with Unilever R&D. Email me if you want to know anything :-)
findaphd.com/phds/project/f…

Wonderful hearing Imran Khan talk about the role of DtpT in peptide transport in S. aureus.
Well done on such a brilliant talk 💫
#Microbio24

Hear hear!

To anyone who needs to hear it. I scream it loud: 'Tenderness and kindness are not signs of weakness and despair, but manifestations of strength and resolution. -Khalil Gibran' Don't let anyone dim your light, and your pain in reaction to their aggression is not weakness

Proper group picture at last! This is us 😎
Dr. Lianne Lansink Leon Walther Beth Spink & Josh Van Der Merwe (still twitterless or Xless)
🧫🔬🧬🧪

#NewPaper from Mathieu Cayla and colleagues Biology at York WTCCB Cell Biology Biological Sciences | University of Edinburgh in Nature Communications

Differentiation granules, a dynamic regulator of T. brucei development #parasitology #gene #expression

nature.com/articles/s4146…

😍

Superb work of Sue Vaughan Oxford Brookes University in collaboration with Richard Wheeler and Jack Sunter revealing the distribution of 30 transition fibre proteins in #trypanosome #cilia ! 👏👏👏
journals.biologists.com/jcs/article/do…

We are very proud that the student Lara Lopez Escobar was awarded with a prize for best talk at #BSP2024 . She clearly explained that motile cells may show a poor yield of GEM encapsulation during #scRNAseq experiments.