We are the Jiang Lab located UT Health San Antonio! We are a multidisciplinary lab group interested in basic and translational science relating to how #connexin #channels affect a multitude of cellular processes. #Follow for research and lab updates 😀 #biochemistry #Science #sanantoniotx

Excited to share our latest #publication on Cell & Bioscience “Mechanosensitive piezo1 calcium channel activates connexin 43 hemichannels through PI3K signaling pathway in bone” Check it Out 😀!!! #piezo1 #cx43 #connexins #bone link.springer.com/article/10.118…

We demonstrate that upon mech. stress 💪🏼, increased intracellular Ca2+ activated by Piezo1 regulates the opening of HCs through PI3K-Akt and opened Cx43 HCs, along with Panx1 channels, and ATP-P2X signaling sustain the intracellular Ca2+ signal, leading to bone anabolic func. 🦴!

Reuben Harris, PhD, prof & Chair in the Dept of Biochem & Structural Biology has received a The University of Texas System Faculty STARs award in the amount of $1.5 million to establish his laboratory & assist in developing new pre-clinical models for cancer drug development. bit.ly/3We4tj5

Best wishes for great success and happiness in the New Year 🎆 and Happy Holidays ❄️🎄!!! #2023 #holidayseason #lab #research #grateful

Viva Science SA 2023 will be held on Saturday, April 1st at The Witte Museum from 9am-3pm. Join us for a day full of free fun for the entire family!

So proud of our PhD candidate Xuewei Wang!!!! 😀 @UTHResearch UT Health San Antonio UTSA The UTSA Graduate School @UTHealthBiomed UT San Antonio Research BME UTSA UTSA COEHD 👏🏼

Check out our lastest #publication “The Second extracellular domain of connexin 50 is important for in cell adhesion, lens differentiation and adhesion molecule expression” 😀 #Cx50 #lens #Science Congrats to the incredible team 👏🏼 sciencedirect.com/science/articl…

Another incredible #publication coming out from our group iScience journal “Protein Kinase A Activation Alleviates Cataract Formation via Increased Gap Junction Intercellular Communication” 👏🏼 #cataract #PKA #oxidativestress #hemichannel #lens #gapjunctions cell.com/iscience/pdf/S…

Jiang Lab had a fantastic time at the BSB retreat these past two days! Special kudos to Drs. Rui Hua and Francisca Acosta on winning 🏆 3rd and 1st place poster awards👏🎉 #connexins UT Health San Antonio Research UT Health SA Alumni UT Health SA Grad School of Biomedical Sciences Long School of Medicine Long SOM Office for Research 🎗Greehey Children's Cancer Research Institute🎗

Excited to announce our #latest #publication in #CellReports! We welcome you to share your insights and consider citing our paper if it aligns with your interests. Let’s push the boundaries together! #ResearchPapers #research

The graphical abstract summarized the story in our published paper. Thank you for your attention.#connexin #hemichannel

Thrilled to share our another new publication “Connexin Hemichannels Drive Lactation-induced Osteocyte Acidification and Perilacunar-Canalicular Remodeling” in #CellReports! Please check out the paper regarding how Cx HCs remodel bone matrix during lactation.#bone #lactation🎉

Good news from our lens group. A new published paper”Mechano-activated Connexin Hemichannels and Glutathione Transport Protect Lens Fiber Cells Against Oxidative Insults” in #RedoxBiology. Welcome to get some details for how Cx HCs regulate #oxidative #stress.

Great job Dr Francisca Acosta, thanks for sharing all of your very interesting data! "Connexin Hemichannel Opening in Osteocytes and PGE2 Release: A Mechanism for Reducing Adiposity, Enhancing Metabolic Balance, and Maintaining Lean Mass"

Jiang Lab is super excited to be here at IGJC2024 #igjc2024!!! Francisca Acosta Rui Hua Jean Jiang UT Health San Antonio UT Health SA Grad School of Biomedical Sciences Long SOM Office for Research

Congratulations to the 2024 ASBMR Louis V. Avioli Founders Awardee Lynda Bonewald, Ph.D.! Dr. Bonewald will receive her Esteemed Award at the 2024 ASBMR Annual Meeting in Toronto, ON, Canada, September 27-30, 2024.