Plasma cells can have a variety of inclusions: 1. Snapper-Schneid granules 2. Crystals that resemble Auer rods 3. Dutcher bodies 4. Russell bodies 5. Mott cell = multiple Russell bodies #hemepath

Cobwebs and crystals: I had to clear some cerebral cobwebs first, but I remembered how to calculate an anion gap; it was 32! Young homeless female, nausea/vomiting/AKI (Cr 7). Oxalate nephropathy. She admitted drinking ethylene glycol. Tubular vacuoles and polarizing crystals.

A nod to nodules: Diabetic patient with proteinuria. H&E: Nodular diabetic glomerulosclerosis, next case right? NOPE!!! Extensive amyloidosis (lambda light chain) in glomeruli and interstitium. Not all nodules are diabetic!! This is why I am a silver stain groupie for life.

But to say something like this and then NOT show the biopsy pictures??? That's just CRUEL. #ShowUsTheBiopsy #PathologistsJustWannaHaveFun🤓😂🤓😂

My obsession with Russell Bodies continues… 😂

Russell Bodies… I can never get enough! 😂

Touched by lupus... I know pathologists are constantly thinking about food, but is it just me or does anyone else think of pasta when you see these lupus "fingerprint" structures in deposits?? 😄

We are a rare breed...

Thrombotic Microangiopathy as an Emerging Complication of #Viral Vector–Based Gene Therapy doi.org/10.1016/j.ekir… #KIRReview #TMA

Primary glomerular diseases are rare, hampering efforts to understand underlying pathobiology & to develop safe & effective therapies. Read this Review of pediatric contributions & lessons learned from the NEPTUNE (rare disease network) cohort study. link.springer.com/article/10.100…

A presentation that was a short course on monoclonal gammopathies in itself. Thank you Jean Hou, MD for such a lucid presentation. Always a pleasure listening to your talks ! 2 more days of more GlomCon Hawaii !! Dont miss miss miss out guys! #GlomConHawaii #GlomCon

Management of Paraprotein-Related Glomerulonephritis with rockstar Roger Rodby at #GlomConHawaii 🌺 Panelists: amazing nephrologists Harish Seethapathy & Ladan Zand and a superb renal pathologist Jean Hou, MD ⭐️ Moderating my good friends Sahar Koubar Jorge Gaytan Arocha & Paul E. Hanna, MD MSc 👏🏻

Starting our afternoon discussing paraprotein related GN. Moderating: Paul E. Hanna, MD MSc Jorge Gaytan Arocha Sahar Koubar Path: Jean Hou, MD Panelists: Harish Seethapathy Ladan Zand Speaker: Roger Rodby What a group 😱🌟 #GlomConHawaii

Let’s go! Next up at #GlomConHawaii 🌺 Roger Rodby w/ Ladan Zand Harish Seethapathy Jean Hou, MD Mod: Sahar Koubar Paul E. Hanna, MD MSc Jorge Gaytan Arocha

Proliferative glomerulonephritis with monoclonal gammopathy, organised microtubular deposits on EM 🤩 ‘Streaming bundles’ of immunotactoid Jean Hou, MD #GlomConHawaii @Glomcon

The case discussions paired with these biopsy slides are like peeling back the layers of Paraprotein-Related GN in real-time. Fascinating to watch it all unfold with Drs. Jean Hou, MD Roger Rodby Ladan Zand Harish Seethapathy Sahar Koubar Paul E. Hanna, MD MSc and Jorge Gaytan Arocha guiding the way.

We need to take this show on the road… 😂

Dream team. 🙌