I finally got around to testing HERRO (github.com/lbcb-sci/herro), the new Oxford Nanopore read correction algorithm which takes simplex ONT reads to PacBio-HiFi-level accuracy. I was impressed! Findings are on my blog in a two-part post: rrwick.github.io/2024/07/26/her… rrwick.github.io/2024/07/31/her…

nature.com/articles/s4158… More interactions between CRISPR-Cas and the most-prevalent phage-inhibition system, toxin/antitoxins: CRISPR-Cas takes a phage protein to form a type II TAs (CreP/CreA) that protects cells from phage anti-CRISPR systems.

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Applications are now open for the Workshop on Genomics 2025 in Český Krumlov (5-18 January)! 🙆🏻‍♀️ Spread the word, and do not miss your chance to attend! Deadline to apply: 18th of September. Information and application forms in our website: evomics.org/2025-workshop-… #evomics2025

Job alert! 📢 I am offering a 2-year position for a bioinformatician. 💻 They will have to organise a database and pipeline to analyse antibiotic resistance genes. 🦠 The job is at the Museo Nacional de Ciencias Naturales and is funded by the Spanish National Plan. Contact me if you are interested!

ePhective Therapeutics is looking for phage scientists to join us in the South San Francisco area for an exciting new endeavor!

An anti-anti-CRISPR that is basically a TA-CRISPR system! CRISPR-regulated TA element provides host cells with population-level immunity against Acr-encoding MGEs, which are notably not targeted by any CRISPR spacers. Ay caramba 🧬

Antimicrobial Resistance is a global health crisis fueled by the misuse of antibiotics. LysJEP8  an endolysin derived from phage JEP8 shows impressive antimicrobial activity against ESKAPE group bacteria. It's time to combat AMR! Read more doi.org/10.1111/1751-7…

Please RT‼️I'm recruiting a PhD student for a fully funded 4 year position to study how ongoing biodiversity change alters disease risk in plant communities in the Åland archipelago meadow ecosystem. DL 28 Aug jobs.helsinki.fi/job/Helsinki-D…

I'm thrilled to announce that our department is now currently accepting applications for a tenure track faculty position in Evolutionary Biology! Job link here: tinyurl.com/yc564huk. Come join us in wonderful Fayetteville and Fulbright College of Arts and Sciences!! Please RT!!

Pls repost: In our collaborative effort EvoReSt, have 11 positions on evolutionary #genomics and #evolution of reproductive systems across the tree of life here Uni Göttingen - checkout uni-goettingen.de/de/687607.html and apply here: obp.uni-goettingen.de/de-de/OBF/Inde…

Insights into the ecology of the infant gut plasmidome | Nature Communications nature.com/articles/s4146…

#plasmidLovers #AntimicrobialResistance #plasmids

» phage satellite manipulates the viral DNA packaging motor to inhibit phage and promote satellite spread | Nucleic Acids Research | Oxford Academic academic.oup.com/nar/advance-ar…

So glad to see this out! It was definitely a labor of love, but it has become my new blueprint of how I think about AMR evolution. We aimed to highlight how much we've learnt as a field, and especially, how much we still *don't* know 1/4

Finally printed 📖! Microbial genomics of MRSA CC398, ESBL-producing E. Coli, plasmid and MGE analysis, and some other things. If interested just get in touch and I can share the pdf! 🙏 #microbialgenomics #bioinformatics #AMR

All ready for the SSM 2024! Beautiful venue with amazing views of the city of Bern. #SSM2024 #bern #microbiology #bioinformatics #genomics

If you like plasmids, insertion sequences, and bacterial evolution, you'll like this one! Now published in its fancy journal format. Thanks to everyone involved in the project, especially Jorge Sastre Domínguez, Alvaro San Millan and the funders Becas Fundación "la Caixa". nature.com/articles/s4155…

Happy to have presented our latest results at the Swiss Society for Microbiology meeting. Nice to see so many colleagues/friends and a huge amount of super interesting talks! Wonderful meeting 🙏 #SSM2024 #microbialgenomics #bioinformatics #mrsa

Latest from the lab! PICI and prophage-encoded Tai proteins protect cells by blocking phage tail assembly. Prophages counter with a mechanism allowing tail formation after induction. Defence and counter-defence genes are organised for expression. nature.com/articles/s4146…