Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma: nature.com/articles/s4146…

Congrats to Kaan Boztug, awarded the Novartis Prize for Therapy-Relevant Immunological Research 2025 for his groundbreaking work on personalized medicine in inborn errors of immunity. 🎥Watch his insights in the video below!

New OA Resource: "A single-cell, spatial transcriptomic atlas of the Arabidopsis life cycle" rdcu.be/eBmkU An extensive single-nucleus and spatial transcriptomic atlas of the Arabidopsis life cycle that represents 10 developmental time points in 6 diverse organs.

Many protein complexes that drive key processes in cells are “molecular motors”—assemblies that consume (electro)chemical energy to produce mechanical work. A 2023 #SciencePerspective discusses how insights from biophysical, biochemical, and structural studies are starting to

Polysomes and mRNA control the biophysical properties of the eukaryotic cytoplasm: Cell Reports cell.com/cell-reports/f…

Clarity in science matters! 🧬🎨 After last year’s success, we once again hosted the workshop on “Applying Design Principles to Schematic Figures”, where design expert Sandra Krahl taught our researchers how to turn complex concepts into compelling visual stories.

🧬Our paper about the epigenetic control and inheritance of ribosomal DNA arrays is now online in Cell Genomics (link in first comment👇). rDNA collectively refers to genes that encode ribosomal RNA, the most abundant cellular RNA. We explored variations in rRNA gene copy number

❓Why does a fusion oncogene cause Ewing sarcoma only in certain cells? Hana Bernhardova from the Tomazou Lab at St. Anna CCRI, who recently received the BIF PhD Fellowship, is building a new model from pluripotent stem cells. Details: 🔗 ccri.at/bif-fellowship…

🧬 New review on nanopore base-calling models is out! Congrats to Sonia Cruciani (former Novoa Lab PhD, now postdoc at the Deplancke Lab, EPFL) and Eva Maria Novoa 📖 Read it here:nature.com/articles/s4158… 👏👏👏

The secret to the naked mole-rats’ extraordinarily long life may lie in subtle changes to just four amino acids, researchers report in Science. scim.ag/46SVkot

🧬A new Science Immunology study by CeMM, St. Anna Children's Cancer Research Institute CCRI, MedUni Wien, Med Uni Graz & Rheinische Friedrich-Wilhelms-Universität Bonn uncovers a surprising link between lipid biology & immune defense, with insights for rare immune disorders & cancer immunotherapy. ➡️tinyurl.com/2ant228p 📄tinyurl.com/yrbzt7st

Two back-to-back stories on mitosis led by my incredible postdoc Kruno Vukušić at Ruđer Bošković Institute, in which we challenge the gliding model of CENP-E-driven chromosome congression! Today in Nature Communications doi.org/10.1038/s41467… doi.org/10.1038/s41467…

A telomere-to-telomere map of somatic mutation burden and functional impact in cancer. #T2T #SomaticMutations #CancerGenetics #Genomics bioRxiv Genomics biorxiv.org/content/10.110…

“Zygotene #cilia regulate #meiosis, #germ cell development and #fertility in #zebrafish, mice, and humans” Hebrew University Faculty of Medicine - The Hebrew University IMRIC Zebrafish Rock!

Scientists have developed a bioinspired soft lens that can adjust its focal length automatically in response to varying light levels, similar to a human eye. Learn more in Science Robotics: scim.ag/3Lj1s0C

Airborne laser scanning reveals stone walls stretching several kilometers across Europe's Karst Plateau, on the border between Slovenia and Italy, likely built over 4,000 years ago to herd and corral red deer—a legacy of coordinated hunting. In PNAS: ow.ly/OI7K50Xir5E

St. Anna CCRI is pleased to announce the appointment of Eleni Tomazou and Sabine Taschner-Mandl, two internationally recognized experts, as new Scientific Directors. 🔗Read more: lnkd.in/gKF_cJFM

Visualizing TERRA RNA G-quadruplex unfolding in FUS biomolecular condensates: biorxiv.org/content/10.110…

Members of the Seruggia and Tomazou groups attended “When Development Meets Cancer” at IRB Barcelona this week! 👏 Talks by Hannah Beneder & Ornella Urzì, posters by Tamina Stelzer, Manon Ressaire & Hana Bernhardova, a fantastic representation from both teams!

Check out our latest work on how collided ribosomes activate the MAP3K ZAK! 💫 nature.com/articles/s4158… A fun collaboration with Beckmann Lab