> You’re born alone and you die alone You’re born into the arms of people who love you with the intensity of a thousand suns and you die enmeshed in a lifetime’s worth of intimacy and connection of your own design

Don't forget! AI Brains Q&A session today at 1p ET. You bring questions, we'll bring answers.

Check out the highlights reel from the 2025 Brains accelerator showcase!

Ok, seriously, time for procrastination is over. You’ve done harder things than applying to AI Brains. Knock it out this weekend. Applications for AI Brains close Monday June 16th!

Last day to apply to the AI Brains Accelerator! 12-week part-time program to train future DARPA/IARPA program managers. This is a special cohort focused on AI. I'm not affiliated, but excited that it's happening. Get AI security research done at DARPA! spec.tech/ai-brains

🧬🪦“SRA is the graveyard for sequence data.” Overheard at Speculative Technologies's Nerd Party yesterday.🥳 Sequencing is cheaper than ever, so we generate massive datasets, extract a sliver of publishable insight, and the rest gets buried. It's about time we build a scalable infrastructure

THE LAUNCH SEQUENCE A new collection of 16 essays on how to accelerate AI for science & security: ifp.org/launch The AI revolution is already delivering enormous consumer benefits. But AI progress won't automatically solve humanity's most important problems first. To

5. Ben Reinhardt on how block-grant labs can generate the real-world data AI needs to do science: ifp.org/teaching-ai-ho…

AI is indeed PhD level: I experimented with asking it to write a report for me and am now wasting more time correcting subtly bad/wrong things than I would have spent writing it from scratch. Just like with many grad students.

Applications for the 2026 cohort of the Brains Research Accelerator are now open! 1/

E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves. We discovered

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has

Holy shit, look at this crowd from the Boston No Kings protest. Samuel Adams would be damn proud.

Applications close in one week! If you have what it takes to start an ambitious research program (in any technical discipline!) we want to hear from you.

At the end of the day, it’s people who create science and technology. Dr. Beck Brachman is the founder of IMPRINT, an FRO decoding the immune system.

As govt funding for basic science declines, philanthropy is stepping in to soften the impact. Even with fewer dollars, improved grant selection and greater flexibility could lead to better outcomes. There is broad agreement that basic science funding produces large societal

This week on Complex Systems I'm joined by Ben Reinhardt to discuss how science funding works in the U.S. and what can be done to improve it. complexsystemspodcast.com/episodes/the-e…

Just published Speculative Technologies's yearly lessons and updated hypotheses. Including: - Work that's a poor fit for both venture and philanthropy, - It is so much easier to make progress on ambitious research when you are already doing things. - Deadlines are incredibly powerful.

Do you know an awesome junior project manager who loves science and technology and knows how to get shit done? Please send them my way - we would like to hire them for our Brains accelerator! lava-somersault-a5a.notion.site/Brains-Project…

Give me the protein methods you successfully synthesized in micrograms in your lab- and in a few weeks I’ll send you 5 grams (not medical grade- just manufacturing/research grade) - would you be interested?