🔬 Excited to share our latest work led by An Nguyen: testing whether Horizontal Gene Transfer can make reverse evolution happen. rdcu.be/du8SD NatureEcoEvo School of Biological Sciences, Monash Monash Science Centre to Impact AMR

Check this out!!! rdcu.be/du8SD Massive thanks to my phD supervisor Michael J. McDonald, Tim Connallon, and the co-authors.

Congrats to Alex Couce Alex Couce group at CBGP, a joint institute Universidad Politécnica de Madrid and INIA-CSIC, for your excellent article published today at Science Magazine , you can read it here science.org/doi/10.1126/sc…

Is evolution predictable ⁉️ "Answering this question has profound implications, the greatest being about the predictability of evolution," explains Alex Couce, who heads a lab that studies evolutionary genetics now at UPM.

Alejandro Couce has used a recent massive genetic engineering technology 🔬 "This technology allows exploring the effect, whether good or bad, of all possible mutations along the >4,000 genes of the bacterial genome," adds Alex Couce.

How stable are bacterial genomes as they adapt to an environment? My collaboration with @anuraglimdi, Alex Couce, @RELenski, and Olivier Tenaillon exploring this over 50,000 generations of evolution is out today! 1/ science.org/doi/10.1126/sc…

Awesome new paper from my current supervisor Alex Couce published in Science today! science.org/doi/10.1126/sc…

I’m starting a special interest group with monthly seminars + discussion focused on the role of mut in evo, covering #evobio #popgen #histsci #philsci Upcoming speakers: Peter Lind @DeepaAgashe Grey Monroe, Rose Novick, Alex Klug DM your email to join Please RT

Reversion to metabolic autonomy underpins evolutionary rescue of a bacterial obligate mutualism biorxiv.org/cgi/content/sh… #biorxiv_evobio

1/7 Excited to share our new preprint! Jonathan Friedman Alex Couce We explored evolutionary rescue in microbial communities, focusing on how obligate mutualisms respond to environmental changes. #MicrobialEcology #EvolutionaryBiology

Happy to share our latest manuscript we we study evolutionary rescue in a bacterial mutualism: Reversion to metabolic autonomy underpins evolutionary rescue of a bacterial obligate mutualism shorturl.at/tFNTw Work led by Ignacio J. Melero-Jiménez in collaboration with Alex Couce >>

New preprint from the Couce lab (Alex Couce) on pervasive epistasis in an antibiotic resistance enzyme. Implications for combination treatments in clinical settings - check it out! biorxiv.org/content/10.110…

Experimental evidence that the tipping point behavior of an ecological community can evolve. New work from Chris Blake, Jake Barber, Tim Connallon, School of Biological Sciences, Monash, Monash Science). nature.com/articles/s4155…

Epistasis drives rapid divergence across multiple traits during the adaptive evolution of a carbapenemase biorxiv.org/content/10.110…

Can evolutionary processes alter tipping points and protect ecological communites from collapse? Christopher Blake et al found adaptation of key species can shift tipping points - promoting ecological stability or accelerating collapse. nature.com/articles/s4155… Michael J. McDonald

It looks like I never posted anything (*but see below) on what are probably the most surprising results my lab obtained so far. Anyway, this work—led by an outstanding former PhD student Sarah Ardell in collaboration with Milo Johnson—is now published: science.org/doi/10.1126/sc…

Very pleased to finally share our review on the need for surveillance to cross sectors to tackle infectious disease and antimicrobial resistance 🦠💊These are dual crises we currently face across the One Health landscape. sciencedirect.com/science/articl…

#ResearchCBGP | Novel antibiotic resistance mechanism discovered in an insect-infecting bacterium 🇪🇸 - short.upm.es/fqtr3 🇬🇧 - short.upm.es/hfibd #somosUPM