Delighted to share our paper on PINK1, now out in nature. We structurally characterised the entire activation mechanism of PINK1 using crystallography and cryo-EM. Thank you to everyone who contributed! @komander_lab WEHI (Walter and Eliza Hall Institute) rdcu.be/cDDHl nature.com/articles/s4158…

💜💛🧡 the 6-cysteine proteins in #malaria ? Check out our review by Frankie Mikha Gabriela & Melanie WEHI (Walter and Eliza Hall Institute) WEHI Postdocs 🧵below Plasmodium 6-Cysteine Proteins: Functional Diversity, Transmission-Blocking Antibodies and Structural Scaffolds frontiersin.org/articles/10.33…

Delighted to have presented my first Melbourne Protein Group #MPG2022 student symposium poster alongside Frankie! Thanks Monash Institute of Pharmaceutical Sciences for hosting us! Sweet surprise at the end and congratulations to the other winners! ✌🏽 WEHI (Walter and Eliza Hall Institute) Wai-Hong Tham #Nanobodies #Malaria

Today in partnership with EMBL-EBI, we’re releasing predicted structures for nearly all catalogued proteins known to science, which will expand the #AlphaFold database by over 200x - from nearly 1 million to 200+ million structures: dpmd.ai/AF-22-TW 1/

"The greatest scientists are always artists as well" - Albert Einstein. Step inside the #ArtOfScience interactive online exhibition, now open! wehi.edu.au/artofscience

Getting to share the night with these wonderful PhD students and RAs - thank you for letting an oldie sit with you! WEHI Postdocs WEHI (Walter and Eliza Hall Institute)

An achievement! Our lab photo and with our friends at Centre of Biologic Therapies #WEHI_Ball #Vibes #WomenInSTEM WEHI (Walter and Eliza Hall Institute) WEHI Postdocs

Congratulations to Niva! Successful completion of a stellar 🌟 Honours 🌟 project on blood brain barrier and nanobodies supervised by Gabby Watson and Jaison Dsa 🤣😂- she brought in the best farewell treats for the lab! So sweet 🍩 🍩 WEHI (Walter and Eliza Hall Institute) WEHI Postdocs

Please RT - We are looking for a wonderful scientist to join our team ⁦WEHI (Walter and Eliza Hall Institute)⁩ - if you are excited about #Proteins #Nanobodies #PhageDisplay please check out this position ⁦🦙🦙 Research Assistant - Protein Production wehi.wd3.myworkdayjobs.com/en-US/WEHI/job…

🌟Annual lab photo 🌟 - wonderful to have three PhD students join the team this year! No lack of artistic talent WEHI (Walter and Eliza Hall Institute) with Lyn Deng from Centre for Biologic Therapies creating a wonderful team portrait of our lab and CBT friends 🦙🧠 🦟 🦠 #WomenInSTEM #ArtScience

We've successfully completed the Single Particle cryoEM data processing workshop. Thanks to everyone. Bio Hamish Brown ARC CCeMMP Matthew Belousoff Australian Research Council Thermo Fisher

Fun first day ourANU Science & Medicine at ANU - very excited to start new infectious diseases projects & ANU #Nanobody Facility 🐸 🦙 - touring Tham lab space with my team WEHI (Walter and Eliza Hall Institute) + our friends Biomolecular Resource Facility - ANU - all bodes well when Division Head takes a great welfie! #Science #Collab

We are here ASBMB Conference 2023 !! Come and visit our posters 32 37 66 69 70 71 if you are excited by #Nanobodies #Malaria #Coronavirus -we would love to chat with you! #ASBMB2023 #Science WEHI (Walter and Eliza Hall Institute) WEHI Postdocs

Last day of #ASBMB2023 - some exciting things for me: geographical landscapes, Fab + 60 kDa + nanodics #cryoEM, plant immunity, ticks and their saliva, ribosome display - looking forward to Biomolecular Horizons 2024 🌟 Fun hanging out with WEHI (Walter and Eliza Hall Institute) team on my first week ourANU 🧑🏻‍🔬

Beaut Weather MAM Conference 🌞 🏖️ 🏄‍♂️ #Malaria #Nanobodies WEHI (Walter and Eliza Hall Institute)

Interested in #malaria transmission? Check out our new work using cryo-EM of ENDOGENOUS sexual stage parasites to determine the Pfs230-Pfs48/45 fertilisation complex - please read & share! structures| nanobodies | human immune responses | mRNA-LNP biorxiv.org/content/10.110…

Stabilized PvRBP2b variants - fun collab + Sarel Fleishman 🔥Increased yields & thermal stability ✌️Maintains human mAb recognition 🩸Sensitivity as sero-diagnostic for P. vivax 💕 Editors Pick 👨🏻‍🔬First paper PhD student Jaison Please read & repost! jbc.org/article/S0021-…

Excited to share our latest work on stabilizing PvRBP2b, a key step toward P. vivax malaria diagnostics! Huge thanks and congratulations to my incredible co-authors and collaborators! Honoured that this is my first PhD publication with Wai-Hong Tham Phillip Pymm jbc.org/article/S0021-…

Pfs48/45 nanobodies block transmission 🦟 Pfs48/45 Nb-Fc reduce oocysts 💎 Structure of transmission-blocking Nb with Pfs48/45 👐🏽 Bispecific Nb-Fc targeting Pfs230 and Pfs48/45 🧑🏻‍🔬 PhD student Frankie Lyons 1st Author 🥳 Please repost & happy reading! biorxiv.org/content/10.110…

Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕 🦟 Transgenic parasites without Pfs230 D13D14 do not transmit 🦙 💉Nanobodies + mRNA induced antibodies reduce transmission New in Science Magazine science.org/doi/10.1126/sc… #ScienceResearch #Malaria