Shobhit jadhav
@jadhav_shobhit
anaesthesiologist. indian
ID: 182920050
25-08-2010 18:33:43
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Sodium-Glucose Cotransporter 2 Inhibitor With and Without an Aldosterone Antagonist for Heart Failure With Preserved Ejection Fraction: The SOGALDI-PEF Trial: JACC Journals 🥸Nice work. 😱Summary 👇👇👇
Miyuru Fernando No consensus. Here's the PK exercise. CMax 1 gm = 140, 2gm = 250 mcg/ml. T1/2=6hr. Time 0: 140 mg/ml or 250 mcg/ml Time 6: 70 or 125 Time 12: 35 or 62.5 Time 18: 17.5 or 31.25 Time 24: 8.75 or 15.625 Compare to MIC, factor in real-world variability. 1 gm probably ok usually.
A time came in my life when I found myself at the bottom of a ditch, professionally and personally. My qualifications still mattered on paper, but the world had moved on. Friends had vanished, recognition had faded, and the future felt sealed shut. In that low moment, I resolved