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Finally we are happy to announce our Soapbox Science #Munich #Online event on 27th & 28th of June, from 7pm onwards! 📅 We will have engaging talks from fabulous #scientists speaking about various topics such as artificial mini-organs, drug design and space telescopes🧫💊🔭 1/4

Out today Cell Reports : first #CRISPR paper from our lab ISD Research @LMU_Uniklinikum Universität München. We reveal frequent and deleterious on-target effects after CRISPR editing in human #iPSCs and describe broadly applicable detection methods. cell.com/cell-reports/f… Thread 👇

Very excited to share our paper published today Cell Reports hopefully contributing to increased reliability of #CRISPR editing. Huge thanks to Joey Kroeger @rainermpg JulienKlimmt Dennis Crusius Angelika Dannert Martin Dichgans and Dominik Paquet cell.com/cell-reports/f…

Nice study from Niakan Lab showing frequent loss-of-heterozygosity and other deleterious on-target effects in #CRISPR-edited human embryos biorxiv.org/content/10.110… - very much in line with our recent study in human #iPSCs cell.com/cell-reports/f…

Check out my JRNLclub talk about our recent Cell Reports paper on on-target effects after #CRISPR editing. Because „Why shouldn’t all publications come along with a thoughtful ten minute talk?“

Curious about large on-target deletions caused by #CRISPR-Cas9 and #DNArepair? Want to learn about locus-specific repair? Look no further than our recent bioRxiv with Felicity R. Allen & Allan Bradley (biorxiv.org/content/10.110…) and a short intro below 👇

BREAKING NEWS: The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”

Christoph Klein, Dominik Paquet Dominik Paquet, Silke Robatzek, Eckhard Wolf Universität München, and Alison Abbott Alison Abbott, nature will discuss whether CRISPR/Cas is just a new tool or a revolutionary method. Join us on February 11 at 7 pm CET. Please register @[email protected].

Happy to share our new paper out in Nature Protocols. We provide a simple and broadly applicable protocol for reliable detection of deleterious on-target effects after #CRISPR editing. Very grateful to Dominik Paquet, @rainermpg and all other coauthors. 👇

#FeaturedProtocol this week by Dominik Paquet Universität München to identify #CRISPR-induced on-target effects using a combination of quantitative genotyping PCR and SNP #genotyping go.nature.com/3siJDQS

Looking forward to interesting talks and discussions at #VKSOmicEngineering21!

Very happy to be at the virtual AD/PD - Advances in Science & Therapy #ADPD2021! JulienKlimmt and Angelika Dannert from the lab are presenting posters describing our work on #CRISPR edited #iPSC based brain tissue models of #Alzheimer’s disease and #Tauopathies. Check them out if you are attending!

I feel very honored that I was selected to give a short talk today at #NYASciences to present our work on #CRISPR-induced on-target effects. Join us today: nyas.org/events/2021/we…

link for free access to our recent Nature Protocols paper ‘Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping’: rdcu.be/chAJ3 Isabel Weisheit Universität München @LMU_Uniklinikum ISD Research @DZNE_en @SyNergy_Cluster Institute of Developmental Genetics

📢Come join us with your friends on July 24 at Max Joseph Platz for a fun science evening! We are grateful to all our sponsors for making this event possible. Universität München (GSN), QMB Munich, @SyNergy_Cluster, @DZNE_de, ChromoTek Airbus, TU München, BESA GmbH & RTG 2175

I’m excited to share that I have successfully defended my PhD thesis recently. I’m very grateful for the support I have received over the last 4 years, especially from my supervisor, Dominik Paquet, and my team members. It has been an amazing journey at the Dominik Paquet. #PhDone

Latest research published in Nature Communications advances #CRISPR gene editing for precise DNA insertions. know.az/3NlLDTG