Mechanical activation opens a lipid-lined pore in OSCA ion channels | Nature doi.org/10.1038/s41586…

Structural insights into ion selectivity and transport mechanisms of Oryza sativa HKT2;1 and HKT2;2/1 transporters | Nat Plants doi.org/10.1038/s41477…

Conformational changes in the Niemann–Pick type C1 protein NCR1 drive sterol translocation | PNAS pnas.org/doi/10.1073/pn…

Our 2025 International Award goes to Prof Renae Ryan at Sydney Science! Prof Renae Ryan is internationally recognised for her work elucidating the fundamental molecular mechanisms of transport proteins, ultimately transforming our understanding of transport across the cell membrane

Thank you to Biochemical Society and my nominators for this award! Science is a team pursuit and this award recognises the hard work of the talented students, early-career researchers & collaborators I am fortunate to do science with! Sydney Health #TransporterBiologyGroup

"A structural biologist's dream" is the caption of this Figure 😉 From a beautiful new review of cryo-EM for structural and cell biology nature nature.com/articles/s4158…

Transport mechanism and pharmacology of the human GlyT1 cell.com/cell/fulltext/…

An exciting time in Solute Carrier research. Here are some of the areas where SLC structural biology is heading and where future opportunities for new discoveries and therapeutic interventions await. rdcu.be/dE759 nature.com/articles/s4159… Department of Biochemistry at Oxford University Kavli Institute for Nanoscience Discovery, Oxford

Excited to share our study on a high-affinity choline and ethanolamine transporter, FLVCR1, published today at Nature. I am grateful for my doctoral advisor ,Hite Lab , my co-authors and collaborators, Tim Kenny, Artem Khan, and Kivanc Birsoy. doi.org/10.1038/s41586…

(1/8) Do you eat enough choline? Have you even heard of it?? Choline is super important for the brain and must come from your diet 🐟🥚🥦 Here nature we show that FLVCR2 transports choline into the brain and use #cryoEM to show how! 🧠🔬 Filippo Mancia nature.com/articles/s4158…

Important findings on the LAT1/4F2hc heterodimer super complex formation from Robinson/Zhou labs. Super updates on the SLC7 family. PE binding sites verified with MS! nature.com/articles/s4146…

Substrate binding plasticity revealed by Cryo-EM structures of SLC26A2 nature.com/articles/s4146…

🎉 Exciting news! Our final manuscript is now published in Nature Communications! 📄 We reveal that the orphan human SLC22A10 gene is a unitary pseudogene due to a fixed missense mutation (P220), while its orthologs in great apes (L220) are capable of transporting sex steroid conjugates.

A wonderful May issue of the International Transmembrane Transporter Society newsletter 🗞️is out: it's packed with lots of important updates & info on #transporter meetings, open positions, papers and much, much more! Click below👇& enjoy reading it!! Transporters and Solute carriers RESOLUTE - Research Empowerment on Solute Carriers LS2 section "Ion Channels & Membrane Transporters" ittsociety.org

Cryo-EM structure of ACE2-SIT1 in complex with Tiagabine | Journal of Biological Chemistry jbc.org/article/S0021-…

Honored to have our work with Alessandro Bonifazi Dr. Amy Newman @BarbaraSSlusher and others as #paperofthemonth and cover by Diabetes, a research journal of the ADA 🧪! We created new drug tools to study how #dopamine in #brain vs #pancreas regulates blood sugar. Pitt Psychiatry NIDDK doi.org/10.2337/db24-0…

Human XPR1 structures reveal phosphate export mechanism | Nature doi.org/10.1038/s41586…

📣 📣 📣 We are excited to announce that registration and abstract submission are now open for the 3rd ITTS meeting to be held Oct 29 - Nov 1 at the NIH campus in Bethesda, MD! See website 👇 for program and further info. ittssymposium.vfairs.com

Glad to share that our review article on SLC6A1 variants (#GABA #transporter 1) in epilepsy is out today: frontiersin.org/journals/molec… Nikita Shah, Ameya Kasture, @SitteHarald, MedUni Wien, Transporters and Solute carriers, International Transmembrane Transporter Society

Repeat after me: LAB WEBSITES MATTER! While it may seem like a nice-to-have... in today's world, it's a need-to-have. For you, your trainees, and your prospective team members. I couldn't have written this better myself: nature.com/articles/s4225…