I couldn't be more excited about our recent publication on the Journal of Extracellular Vesicles (Highest honor for EV research). Navneet Dogra Icahn School of Medicine at Mount Sinai ISEV-Journals ISEV Lipschultz Precision Immunology Institute #ExtracellularVesicles #ncRNAs #noncoding #intergenicregions #snoRNAs #snRNAs

Navneet Dogra Icahn School of Medicine at Mount Sinai ISEV-Journals ISEV Lipschultz Precision Immunology Institute In this study, we also show the importance of following misev2023 guidelines between 3 different methods to isolate EVPs. doi.org/10.1002/jev2.1… Identifying EVPs isn't hard, but factors affecting the isolation can significantly impact the type of vesicle isolated,

Excited to share our new publication ISEV. #Prostatecancer, the second leading cause of cancer in men, is diagnosed with a #biopsy. We discovered new #RNA "darkmatter" in blood #ExtracellularVesicles, that changes pre-/post-surgery. #Liquidbiopsy pubmed.ncbi.nlm.nih.gov/39148266/ 1/8

🆕New in #JExBio🆕This study provides the first comparison of young and old skeletal muscle EVs to map changes associated with SM ageing. These data suggest SM-EVs could provide an alternative pathway for homeostasis and detoxification during SM ageing isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

🆕New in #JEV🆕This study explores the role of Roseburia intestinalis-derived EVs as potent anti-inflammatory mediators in treating DSS-induced colitis, shedding light on the impact of BEVs on intestinal recovery and gut microbiome in treating IBD. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

🆕New in #JEV🆕 This urinary EV-based prostate score model demonstrated a potential reduction in unnecessary prostate biopsies by 26%, with only a 3% miss rate for clinically significant PCa cases, indicating its effectiveness in the Chinese population. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

🆕New in #JExBio🆕This study characterized MVs derived from Lacticaseibacillus rhamnosus CCM7091 isolated at different growth stages showing that MVs derived from the late stationary phase boost the immune response most effectively. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

🆕New in #JEV🆕This review focuses on #EVs released during exercise, discussing putative stimuli that may trigger EV release, their biological functions and the impact of exercise-induced EVs on cancer development and progression. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

🆕New in #JExBio🆕A suite of single-particle resolution methods were used to determine the loading of rhodamine 6G with 4 common loading methods - quantification metrics can impact conclusions & single-particle characterization of EV loading is important. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

👏New in #JEV👏An aptamer-guided fluorescence polarisation platform for extracellular vesicle liquid biopsy - a simple method that could be implemented on automated biochemistry analysers for real-time cancer monitoring. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

📢New in #JExBio📢Monocyte derived large EVs were significantly higher in polytrauma patients with internal organ damage suggesting serum-derived AnnV+CD14+ large EVs could serve as a supportive tool in decision-making in polytrauma situations. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

🎉Read in #JExBio🎉Engineered extracellular vesicles coated with an antimicrobial peptide for advanced control of bacterial sepsis. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

😃Read in #JEV😃 A Q225P substitution in the alternative sigma factor B triggers MV production in Staph. aureus strain Newman by hindering the specific binding of SigB to the asp23 promoter, thereby repressing expression of alkaline shock protein 23. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

📚Read in #JEV📚The findings presented here highlight the utility of optimized polysaccharide chitosan-based magnetic beads for sEV isolation for identifying early detection biomarkers in HBV-HCC. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

📚Read in #JExBio📚Profiling biomanufactured extracellular vesicles of human forebrain spheroids in a Vertical-Wheel Bioreactor. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

📢CALL FOR APPLICATIONS FOR ASSOCIATE EDITORS - CLOSING SOON📢Both of our Journals are currently looking to expand their Editorial Board and are calling for applications for the role of Associate Editor. Closing date for applications is September 8th 2024! isev.org/associate-edit…

🆕New in #JEV🆕 The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress. Read the full text here 👇isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

Congratulations to our colleagues from the Laboratory of Intercellular Communication for their latest article in Journal of Extracellular Biology!  ISEV-Journals doi.org/10.1002/jex2.1… #czesev #extracellularvesicles

🆕New in #JExBio🆕These authors established a method to obtain functional chondrocyte-derived EVs before, and during, cartilage mineralization that may aid the further understanding of their roles in endochondral bone growth and fracture healing. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…

📢New in #JExBio📢 This review delves into the importance of EVs in reproduction, explores current techniques for in vitro EV production and the potential of bioengineering technologies to establish innovative systems for enhanced production. isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…