After a virtual kickoff in January, now followed by F2F meeting in Turku, plus an open minisymposium on 26.4. with several of our PIs as guest speakers. #immunity #exposome #MultiOmics #metabolomics #gutmicrobiome #systemsbiology

Busy 1st day INITIALISE kickoff in Turku. Setting up #multiomics longitudinal studies across multiple birth cohort studies, with many different outcomes, is quite challenging, but we are well on the way. Now time for 1st consortium dinner! TurkuBioscience InFLAMES Flagship

INITIALISE kickoff was followed by minisymposium yesterday, featuring several of our visitors (INITIALISE PIs), opened with lecture by A.Zhernakova. Series of highly interesting lectures on early-life factors impacting life-course health. TurkuBioscience InFLAMES Flagship

Researchers TurkuBioscience and InFLAMES Flagship have identified a gene expression signature that can predict the progression of type 1 diabetes. One benefit of such predictive signature could be the ability to intervene earlier in the disease process. utu.fi/en/news/press-…

The #COVID19 SARS-CoV-2 new onset Type 1 #Diabetes #T1D epidemiology saga keeps unfolding "There was an increase in T1D incidence during April–June 2021 compared with April–June 2015–2019, but this could not be attributed to SARS-CoV-2 infection" diabetesjournals.org/care/article/d…

Excellent review by Clare Lloyd Lab NHLI & Sejal Saglani NHLI Centre for Paediatrics & Child Health on early life interactions btw a developing immune system, colonizing microbes and protective/damaging environmental factors with longterm consequences for lung health: nature.com/articles/s4159…

Our INITIALISE recruits TurkuBioscience arrived (from left): Pauli 🇫🇮 (Postdoc, #multiomics, #visualization), Abhijit 🇮🇳 (Postdoc, #GSMM #computationalbiology), Anastasiia 🇷🇺 (Lab engineer #metabolomics), Ziyu 🇨🇳 (PhD student, #immunometabolism, #fluxomics).

Santosh Santosh Lamichhane from our #systemsmedicine team TurkuBioscience Turun yliopisto - University of Turku showing longitudinal data on novel #bileacids conjugates in infants at risk for #T1D (vs. age & islet autoantibody positivity) #NMetC2023 #metabolomics #lipidomics Pieter Dorrestein

Welcome to next Nordic #metabolomics conference #NMetC2024, which will be in Turku 🇫🇮, August 26-28, 2024. Local org co-chairs ⁦Alex Dickens⁩ (presenting here about the mtg), ⁦Kati Hanhineva⁩ and myself. #NMetC2023

Brain #lipidomics with timsTOF, indeed exciting times ahead for #MSimaging applications TurkuBioscience InFLAMES Flagship #metabolomics #proteomics

A great conference coming up FREIA INITIALISE partners will be attending. I have registered. "The impact of endocrine disruptors on early development and reproductive health" More information: COW2024.dk

Good scientific start of the year: the study led by my friend and colleague Jingyuan Fu is published in nature! This work is focused on deletions and duplications of microbial genes and how they are related to human genetic variants. groningen_microbiome UMCG Genetica Lifelines

Happy to share new paper of ours, published in The Lancet Planetary Health thelancet.com/journals/lanpl… Cudos particularly Tuulia Hyötyläinen aodhan.mcglinchey Paul Fowler INITIALISE

'Forever chemicals' found in foetuses pose risk of adulthood diseases – Euractiv euractiv.com/section/health… nice to see Euractiv picking up on our study Matej Oresic UoA Medicine, Medical Sciences and Nutrition University of Aberdeen Matej Oresic Tuulia Hyötyläinen aodhan.mcglinchey INITIALISE

Amazing development, 65 fully funded PhD positions will soon open in the area of #immunology (incl #diagnostics #immunometabolism etc) in Turku. ⁦INITIALISE⁩ inflames.utu.fi/inflames-sai-t…

Great annual INITIALISE meeting in Naples. Great progress, publications, and much more to come this year. Welcome also to new project partner GENOS Glyco Gordan Lauc #immunesystem #multiomics #gutmicrobiome #exposome #HorizonEurope

Lots happened INITIALISE since it kicked off. 2 new partners, papers in top tier journals (including one coming out soon), this year large scale #multiomics studies being initiated (incl #glycomics, new addition), mechanistic studies in high gear. Next year mtg in Stockholm.

Day 2 of #IMMEDIATE progress meeting in Milan with partners joining in person and online. We started with a presentation by Alex Dickens, who presented the work of our sister project INITIALISE. Continuing with workshops to discuss the details and needs of each work package.

Exposure to environmental toxicants is associated with #gutmicrobiome dysbiosis, #insulinresistance and #obesity. Suomen Akatemia | Research Council of Finland sciencedirect.com/science/articl… #exposome #metabolomics #bileacids #metabolism More soon INITIALISE

Excited to be involved in this study from ABIS cohort, just published in Cell, on #gutmicrobiome & metabolome preceding neurocognitive disorders. Super kudos to Angelica Ahrens, Eric Triplett & Johnny Ludvigsson. #metabolomics #autism #ADHD INITIALISE shorturl.at/ayzBT