Tim Raine
@IBD_MB
Consultant Gastroenterologist & IBD lead Cambridge University Hospitals, UK. ECCO Guidelines & UEGW Scientific Committees. Clinical trials & mucosal immunology.
ID:948695226264293378
03-01-2018 23:19:02
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It’s finally here! The latest “cheese and onion”. Delayed by a pandemic that gave us all other things to focus on. Well done and thanks to all my co-authors and special thanks to the team OUP Medicine
Fantastic work Monika Krzak Tobi Alegbe Leland Taylor and team. Pleasure to cosupervise with Carl Anderson. Large (n=120 participants) scRNASeq atlas of Crohn's ileum. Hope useful public resource. Novel findings incl. upregulation of epithelial MHC-I & Ag processing machinery
Was pleasure to write this piece in Nature Reviews Gastroenterology & Hepatology with talented Nuru Noor. We argue not just for structural changes to phII trials in IBD but exploiting scientific advances &leveraging existing data to offer new endpoints hence more precise&efficient trials & ⬇️placebo