Our protocol for a million-spot peptide binding array designed on a DNA sequencing chip. star-protocols.cell.com/protocols/2136 This is part 2 of 2 describing the nuts and bolts of ProtSeq doi.org/10.1016/j.isci…

Interest in RNA editing is exploding, as a growing cluster of firms is harnessing an endogenous enzyme, adenosine deaminase acting on RNA (ADAR), to edit mRNA transcripts nature.com/articles/s4158…

Foldseek, our fast structural aligner, is now published Nature Biotechnology. It allows you to search through large structural databases like #AlphaFold or #ESMatlas in seconds. A long journey since '18! 1/6 📄nature.com/articles/s4158… 💾foldseek.com 🌐search.foldseek.com

A fully integrated wearable ultrasound system to monitor deep tissues in moving subjects go.nature.com/43iV4dK

New in Science: MRI data from more than 40,000 UK Biobank participants reveals the intertwined nature of heart and brain health in humans. The results could help identify new potential therapeutic targets. scim.ag/2UK

The investigators describe antibodies that bound amyloid in three patients with transthyretin amyloidosis. Spontaneous regression of cardiomyopathy occurred in all three patients. nej.md/3oGAPIo

Since the discovery of CRISPR-Cas systems, people have wondered if a similar type of system exists in eukaryotes. Today, we report in nature the characterization of Fanzor, a eukaryotic RNA-guided system that can be reprogrammed for human genome editing. nature.com/articles/s4158…

A general thread on what Perturb-seq is, what it's good for, and how we managed to reduce its cost by an order of magnitude in our recent work: 1/33

Metabolites and RNA in a tissue section are profiled simultaneously go.nature.com/45Rms4l

So excited to come home to San Diego for cardiology fellowship!🫀🧬 UC San Diego Cardiology UC San Diego Cardiology Fellows

We are extremely proud to welcome our newly matched general cardiology fellows! Welcome to the UC San Diego Cardiology Fellows family! Jessica Hong Emily Margolin, MD Rebecca Ocher Anna McDivit Mizzell, MD, FACC Harpreet Bhatia

Sudden ST changes on telemetry prompt a 12-lead ECG for a critically-ill patient who is intubated, sedated, and paralyzed. What would you do next? ja.ma/3Rc7YWh Jessica Hong

What would you do next? Your intubated ICU patient develops acute, diffuse ST elevations after neuromuscular blockade. Check out our JAMA Cardiology case Marcella Press MDPhD #ecg #CardioEd jamanetwork.com/journals/jamac…

Our latest nature paper is out! We show that transplanting mitochondria into endothelial cells boosts their ability to form blood vessels in ischemic tissues, with mitophagy as the key mechanism. A potential game-changer for vascular cell therapies. nature.com/articles/s4158…

Nature research paper: Temporal dynamics of the multi-omic response to endurance exercise training go.nature.com/3QtJ6Km

New publication nature from Dr. Kevin King and Dr. Van Ninh: Spatially clustered type I interferon responses at injury borderzones Eric Adler UC San Diego Cardiology Fellows UC San Diego Health Sciences nature.com/articles/s4158…

Incredibly exciting to see Dr. Hsue, brilliant physician scientist and woman, at the helm! 🙌🫀

Cool tech here, imagine the potential applications

Amazing capability of nanopore for amino acid sequencing

👏 👏 well deserved!