🧵1/ Excited to share our new preprint! “Complete Enzyme Clustering Enhances Coenzyme Q Biosynthesis via Substrate Channeling” A collaboration between Shakhnovich Lab and MatteviLab Read on bioRxiv: biorxiv.org/content/10.110…

Whitehead Institute and Harvard researchers have developed Perturb-Multi, a powerful new approach that simultaneously measures how genetic changes, such as turning off individual genes, affect both gene expression and cell structure in intact tissue.

Check out our latest work, in collaboration with the Montemore group, on tuning one-pot reaction selectivity in dilute PdAu alloy catalysts! Harvard Chemistry Harvard SEAS

Check out our lab's newest pub, live in ACS ChemBio! We report interesting CRBN-independent activities of N-alkylated lenalidomide derivatives, or "capped imides." Congrats to Farah and all of the authors! 🥳💐 pubs.acs.org/doi/10.1021/ac…

New paper in PNAS! With Shakhnovich Lab Harvard Chemistry , we built VIRAL: a few-shot active learning framework to predict dangerous viral protein variants before they spread. pnas.org/doi/10.1073/pn…

At Chem Catalysis, we worked with Sautet group UCLA Chem & Biochem to study electron storage at the Au/anatase-TiO2 interface Harvard SEAS Harvard Chemistry kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

New: A startup's solution to surging AC use in a hotter world developed with Aizenberg Lab #research "Novel system works like a coffee filter to dry, cool air more efficiently" #chemtwitter news.harvard.edu/gazette/story/…

In Nature Communications, we report how the sequence of preparing Pd8Au92/SiO2 catalysts tunes the size of Pd ensembles on the nanoparticle surface Harvard Chemistry Harvard SEAS UC Merced Northwestern Stony Brook University Materials Intelligence Research @ Harvard Christian Reece Faculty of Science, Utrecht University Aizenberg Lab nature.com/articles/s4146…

Feels very appropriate to be in Germany as my first paper with the Nocera Lab is on the web in Angewandte Chemie🇩🇪🧪. I had a ton of fun working with the Silver Dream Team on this project🥈, so please check it out! onlinelibrary.wiley.com/doi/10.1002/an…

New from Richard Liu's Lab #chemtwitter

Check out our microfluidics-based strategy for shaping LCE microactuators into various 3D shapes in Adv. Mater., led by Milan, Hamed & Peiyuan (Tony)! Harvard SEAS Harvard Chemistry advanced.onlinelibrary.wiley.com/doi/10.1002/ad…

Our group reports a Ni-catalyzed desulfurative ring contraction method in J. Am. Chem. Soc.. By performing double SNAr reactions and "deleting" the sulfur atom afterwards, many fun heterocycles can be synthesized in 2 steps from commercial materials. Congratulations, Jianhan (Johnson) Zhou!

It was a pleasure collaborating with Marian Huot, Vaibhav Mohanty, PhD , and the Shakhnovich Lab at Harvard Chemistry to model pandemics and develop defenses against evolving biological threats. Check out the coverage here! news.harvard.edu/gazette/story/…

🚨My first solo paper out in J. Am. Chem. Soc.! 🚨 We deleted sulfur from a range of S-heterocycles (C, Si, O, N) using Ni catalysis. 🔧 Avoids catalyst deactivation! 🔁 Offers a unique retrosynthetic disconnection! pubs.acs.org/doi/10.1021/ja… Harvard Chemistry Richard Liu #JACS

New #research from the Keutsch Lab: "Mitigation of Indoor Ozone and Secondary Products from 222 nm Germicidal Ultraviolet Light Using Commercial Air Cleaners" | ACS ES&T Air pubs.acs.org/doi/abs/10.102… #chemtwitter

Today in Cell we report the use of prime editing to correct several mutations that cause alternating hemiplegia of childhood (AHC), a rare and devastating neurodevelopmental disorder, in patient-derived cells and in two mouse models. drive.google.com/file/d/1ibC50t… 1/10

Adding to the growing toolbox of aryl azide syntheses: From Shangyu Li on ChemRxiv, Pd-catalyzed coupling of ArBr/ArOTf with NaN3. This reaction is trickier than it looks: as we show, [LPd-N3]2 dimers form with many L's & the pdt can inhibit Pd(0). doi.org/10.26434/chemr…

In Nature Chemistry, we report reversible hydroxide emitters that generate highly basic (pH ~13) solns under light & revert to neutral in dark. The compounds, taking advantage of aromaticity effects, can directly capture/concentrate CO2 from ambient air. rdcu.be/eAB2S

Why sulfur is important in lincosamide antibiotics. Check out this collaboration btw Harvard Chemistry & UIC Department of Biological Sciences in Chem #ACSFall2025 hubs.li/Q03zNywc0

A Unified Picture of Radical Anion Photoredox Chemistry | Journal of the American Chemical Society Harvard University pubs.acs.org/doi/10.1021/ja…