Huge congratulations to my collaborator and partner in crime Hannah Bell on her successful thesis defense. She's a #superstar

Hyping new Science Immunology from Hanna Hong (before #Twitter burns down 🔥) ➡️OXPHOS Promotes Apoptotic Resistance and Cellular Persistence in TH17 cells in the Periphery and Tumor Microenvironment ⬅️ Read on for a #tweetorial science.org/doi/10.1126/sc…

Excited to share cool findings in our recent article. Amino acid sensing complex, GATORs were first discovered by Liron Bar-Peled and David M. Sabatini group. 1/6 # We show that colon tumors deregulate GATORs to boost mTORC1 and drive tumors in vivo.

Thank you U-M Rogel Cancer Center for highlighting our work, and thanks again to Cell Metabolism. Congrats Hannah Bell and all of the authors and collaborators.

Excited to share our recent findings! Sulfide oxidation promotes hypoxic angiogenesis and neovascularization biorxiv.org/content/10.110…

Just read this new paper at Cell Press. Nice study validating many results my amazing lab mate Hannah Bell found in CRC with regards to the roles of L. reuteri in antitumor immunity, AhR signaling and microbial metabolites. cell.com/cell/fulltext/…

🔥Hot paper alert 🔥 New one from Zeribe Nwosu, Matt Ward, Peter Sajjakulnukit, Pawan Poudel, et al. out today nature #OpenAccess Buckle up for the tweetorial 1/n nature.com/articles/s4158…

Go Rashi! Rashi Singhal, Shah Lab Speaking on HIF, Fe and cell death

I am delighted to introduce Chesta Jain, (she/her) latest work. sciencedirect.com/science/articl… Unlike other cell types, macrophages do not require HIF2 to maintain cellular iron levels or systemic iron homeostasis. UMPhysiology U-M Rogel Cancer Center

Excited to share this review from Sumeet A Solanki focused on hypoxia/HIFs in the GI tract. annualreviews.org/doi/10.1146/an… UMPhysiology U-M Rogel Cancer Center

Scott Dixon (@SJD956 ) and I wrote a short guide summarizing issues that affect evaluation of cell death💀Should be of interest to anyone that is exploring mechanisms of drug action, drug resistance, or those aiming to get deeper insights about death regulation. Please read!

Happy to share our new work where we took a deep dive into ER-mito contact sites and metabolic cell bio! Thanks to all the authors and most importantly Shah Lab and Lyssiotis Lab for their support. I will share some snippets of this journey from my perspective (🧵👇) (1/n)

The day has come! Please donate to giving blue day to support a developmental biology short course. Donations between 8-10 am, 5-7 pm, and 9-11 pm have additional matches! Any amount helps! givingblueday.org/o/university-o… #givingblueday

I'm thrilled to share, our work is online now Nature Chemical Biology. Huge thanks to Ruma Banerjee, Shah Lab Costas Lyssiotis and all authors Rashi Singhal Sumeet A Solanki Sydney Alibeckoff Hannah Bell and others.rdcu.be/dBSCb

I'm so excited to have my first PDAC paper online in this preprint! HUGE thanks to my mentors Arul Chinnaiyan Lyssiotis Lab Yuanyuan Qiao, PhD and my research group the PIKfyve BeSTies (P-BSTs)!!

So excited that our review article on the role of ferroptotic cell death in immunity is finally out! Check it out to learn how this iron dependent cell death pathway regulates immune responses in tumors, autoimmunity, infection and homeostasis. Brent Stockwell Immunity