Another exciting discovery from the School of Life Sciences at Peking University- Dr. Jiazhi Hu's group found that the 3D genome architecture ensures the orderly firing of DNA replication origins DOI: 10.1126/science.adj7606

Dr. Jiazhi Hu's group finds that DNA replication forks are consistently coupled together in mammalian cells, resulting in chromatin fountain structures. #PKUResearch Science Magazine science.org/doi/10.1126/sc…

Dr. Xuemei Chen's group finds that Toll/interleukin-1 receptor (TIR) domain-containing proteins can function as NAD-RNA decapping enzymes by releasing the NAM moiety from NAD cap, resulting in the regulation of gene expression. #PKUResearch Xuemei Chen lab nature.com/articles/s4146…

Amazing last few days at UCLA for the plant epigenetic symposium and lab reunion. It was great to catch up with old friends and make connections with new friends!

Interested in #noncanonical #ORFs or #upstream #ORFs? How do your favorite genes look in super-resolution #Riboseq data? Check out our JBrowse tracks on #TAIR. Big thanks to TAIR TAIR @tairnews.bsky.social for hosting our data.

📢 Thermomorphogenesis community 📢 Tuesday next week we will have Prof. Meng Chen (Meng Chen) presenting his published work (co-lead with Prof. Xuemei Chen, Xuemei Chen lab) on miR156 regulation in response to environmental changes. Don't miss out!!

I am proud to announce that the Methods in Molecular Biology issue on thermomorphogenesis is now available online. This collection includes 23 current protocols for investigating how plants perceive and respond to high ambient temperatures. -- link.springer.com/book/10.1007/9…

UTR-LM: A 5′ UTR language model for decoding untranslated regions of mRNA and function predictions nature.com/articles/s4225…

bioRxiv: Transcriptome-wide mRNA condensation precedes stress granule formation and excludes stress-induced transcripts dlvr.it/T5cPhj

Many thanks to Blavatnik Awards for promoting our science! John Innes Centre

How do cells efficiently respond to stress? Transcriptional stress responses are well-known—and in our latest study, we discover that cells use biomolecular condensation to redirect translation from old to new mRNAs 1/n biorxiv.org/content/10.110…

Happy to share our new paper on photobodies -- photobody formation spatially segregates two opposing phytochrome B signaling actions of PIF5 degradation and stabilization. Congrats, Ruth Jean Ae Kim, De Fan, jiangman, Keunhwa Kim, Juan Du! nature.com/articles/s4146…

Dispersed Transcription Start Sites Modulate uORF-Mediated Regulation in Arabidopsis biorxiv.org/cgi/content/sh… #biorxiv_plants

Does phase separation of subnuclear organelles occur randomly? Our study shows that photobodies form via nonrandom phytochrome B condensation at defined subnuclear locations. Congratulations to my brilliant postdocs Juan Du and Keunhwa Kim -- nature.com/articles/s4146…

Global recruitment CEPAMS John Innes Centre UK-China collaboration platform and strong mentoring system!

Norwich RNA Club is a global community of researchers and enthusiasts who explore the fascinating realm of #RNA 🧬 If you would like to be kept up to date on RNA seminars and symposiums, then please sign up to the mailing list 💻✉️: okt.to/ZxdaD1

Excited to share Matt's preprint on Golden Braid-based tools! These innovative methods enhance geminivirus vectors for high-level protein expression and provide repair templates for gene targeting in plants. Check it out and let us know your thoughts. biorxiv.org/content/10.110…

Happy to share our new paper -- HOT3/eIF5B1 confers Kozak motif-dependent translational control of photosynthesis-associated nuclear genes for chloroplast biogenesis. Congrats to all authors, Xuemei Chen lab Meng Chen nature.com/articles/s4146…

I'm so happy to have Brian, a great colleague, on board of the TPC leadership team!

Excited to share our new review on plastid transcription and its regulation by anterograde signaling during chloroplast biogenesis. Congratulations to Nora Flynn Nora Flynn and Xuemei Chen lab. --doi.org/10.1007/978-3-… or plasticgenome.org/wp-content/upl…