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For years, scientists have thought of hunger regulation as a tug-of-war between two types of neurons in the hypothalamus. Now a new study challenges this long-standing model, revealing a third player in the hunger-satiety network. By Giorgia Guglielmi (she/her) thetransmitter.org/appetite-regul…

Glad to see this come out! Congrats to the team. Great mind thinks alike 😄

New content online: Advances in appetite regulation by the arcuate nucleus go.nature.com/4fcoHD2

Excited to share our single-cell study on aging mouse brain published in Nature today! We found an aging hotspot in specific hypothalamic cell types involved in energy homeostasis, which show both decreased neuronal function and increased immune responses. doi.org/10.1038/s41586…

Congrats! Philipp.

We are now accepting applications for 2025 Connexins! This is an in person symposium for senior graduate students to share their works with the NYU neuroscience community. Please RT!!! wp.nyu.edu/connexins/

Antipsychotics are often prescribed to suppress hyperaggression. Do they really suppress aggression or just cause sedation? Antipsychotics target dopamine receptors. Our new study, published today nature, uncovered the role of dopamine in aggression. nature.com/articles/s4158…

Really enjoyed my visit. Thank you for having me!

Join us for the Modulation of Neural circuit GRC this May!

We're organizing the 4th iDISCO / TRISCO workshop at Rockefeller University in NYC! April 14-19 - FREE - register to [email protected]. Deadline: March 1st. We'll talk about brain mapping of cells, genes, axons, vasculature, light sheet microscopy, tissue clearing.

In addition to saving lives, NIH-funded research creates jobs and economic benefits. These are the top 15 states by NIH awards and jobs created. FY2023 data from unitedformedicalresearch.org

Looking forward to my visit!

Check out our latest preprint, where we cross-compared the molecular landscapes of immature neurons in the hippocampus in different mammalian species👨‍🦰🐵🐷🐭, revealing specialized features in humans. biorxiv.org/content/10.110…

On this #WorldObesityDay, we bring you this Special Issue on Obesity, highlighting the complexities of this disease and systemic challenges we must overcome to combat it. cell.com/cell-metabolis…

Today in nature, we share our latest paper. We developed an algorithm to predict novel peptides cleaved by proconvertases across all human tissues. Using this method, we identified BRP, a brain-derived anti-obesity peptide. nature.com/articles/s4158…

30 years after discovering leptin, Jeff Friedman's lab has located a neural mechanism in obese mice that helps explain leptin resistance. In this Q&A, he discusses how dysregulated leptin leads us to put on pounds, new treatments for obesity, and more: rockefeller.edu/news/37460-a-s…

(1/n) Why is it so hard to stop eating when something tastes amazing? Our new Science Magazine paper reveals that dopamine helps sustain our drive for tasty treats—and may explain how anti-obesity Ozempic tames those urges doi.org/10.1126/scienc…

Happy to share this review on glucose and fructose metabolism in Annual Review of Nutrition Annual Reviews. There is still a lot we don’t understand of how fructose metabolism is controlled. Jameel Karen Linde-Garelli Stanford Pathology Stanford Diabetes Research annualreviews.org/content/journa…

Honored and grateful to be back at Hopkins to receive the award- felt like giving another thesis seminar all over again.