One month until the CSHL Biology of Genomes abstract deadline! My all-time fav meeting, and one of the few covering genomics broadly. We have a ✨🤩 lineup of speakers, but it's the abstract talks & posters that make the meeting - send us your best work! meetings.cshl.edu/meetings.aspx?…

Modern GWAS can identify 1000s of hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease? I'm excited to present our new work combining associations + Perturb-seq to build interpretable causal graphs! A🧵

Excited to present our work on developing jaxQTL, a new single-cell eQTL mapping tool that improves power and robustness in identifying sc-eQTLs using count-based models. See details in threads 🧵 medrxiv.org/content/10.110…

1/ I am beyond thrilled to share our new paper in Cell! We explored the regulatory principles underlying pleiotropy in psychiatric disorders. cell.com/cell/abstract/…

The distribution of highly deleterious variants across human ancestry groups biorxiv.org/content/10.110… #biorxiv_genetic

New preprint w/ Soumya Kundu, Anshul Kundaje (anshulkundaje@bluesky), & Stephen Montgomery! Using deep learning & scATAC-seq, we studied context-specific variants in disease & evolution, and introduce FLARE for de novo mutations—with application to autism-affected families. doi.org/10.1101/2025.0…

I've been singing with the Bronx County Chorus since 2015. It's a beautiful, intergenerational community bringing free music to the Bronx since the 1930s. With grants shrinking, they now need support to keep going. If you can, please consider helping: gofundme.com/f/support-the-…

Two new postdoc positions in Computational/Statistical Genomics and Statistical Population Genetics, respectively, at the University of Copenhagen: employment.ku.dk/all-vacancies/… employment.ku.dk/all-vacancies/… . Please help us advertise.

Tehran has upwards of 15M metro population. The roads out have been blocked by traffic all day. Where and how do you think these people will evacuate?! My 72 yo mother is literally there right now, doesn't even have a car. I personally know 100s of people in a similar situation.

I am a son of a former political prisoner in Iran and the nephew of an executed dissident and another political refugee in exile. My family has been subjected to more violence than anyone who is attacking Iran, at the hands of this regime. So it is with zero sympathy for this

It was fun writing this short piece on the omnigenic model. Sharing it here, though it's a painful time as my family, along with millions of others, is at risk in Iran and the region.

Got an email from my PhD student today—she had traveled to Tehran just a few weeks ago, right before war was unfolding. No complaints. No requests. Just a quiet, steady project update—sent with the kind of calm strength that left me speechless. I sat there staring at the

Staff scientist position (computational): I am looking for a computational scientist to join my genomics lab at Stanford. They should have an outstanding skillset in ML/statistical methods for genomic applications, postdoc experience and a strong publication record. #sciencejobs

📣New today! 📄Haplotype analysis reveals pleiotropic disease associations in the HLA region 🧑‍🤝‍🧑 Jonathan Pritchard FinnGen & colleagues cell.com/ajhg/abstract/…

The #GENETICS Primers section is expanding, with Beth De Stasio as Senior Editor and six new Associate Editors joining the team. These guides help bring real research into the classroom. 📢 Browse existing Primers: buff.ly/5GYwj2n

A brief musical note: I’m very excited to share that my brilliant wife, a pianist and composer, has just released her debut album featuring works by Iranian women composers, including one of her own. Here is the link in case you’d like to take a listen: navonarecords.com/catalog/nv6747/