Helix BioStructures (@hlxbio) 's Twitter Profile
Helix BioStructures

@hlxbio

Helix Biostructures is a structural biology CRO providing structure-based drug design services to early-stage through Fortune 500 drug discovery companies.

ID: 1044952880665505792

linkhttps://www.helixbiostructures.com/ calendar_today26-09-2018 14:12:35

314 Tweet

431 Followers

1,1K Following

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In 2 weeks our team will be at the Structure-Based Drug Design Summit in Boston alongside speakers from Pfizer, Sanofi, Takeda, and GSK. More details: loom.ly/A8ejNgw Come and say hi June 3-5!

In 2 weeks our team will be at the Structure-Based Drug Design Summit in Boston alongside speakers from Pfizer, Sanofi, Takeda, and GSK. 
More details: loom.ly/A8ejNgw
Come and say hi June 3-5!
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Working on X-Ray Crystallography and want to get published? Peter Stogios, our Senior Scientist in Structural Biology has published over 80 peer-reviewed scientific articles. Meet him and the rest of our team here: loom.ly/QNjzYck

Working on X-Ray Crystallography and want to get published? 
Peter Stogios, our Senior Scientist in Structural Biology has published over 80 peer-reviewed scientific articles.
Meet him and the rest of our team here: loom.ly/QNjzYck
Helix BioStructures (@hlxbio) 's Twitter Profile Photo

In the Boston-Cambridge area? Come and meet our team in person to discuss your project. We'd love to meet you! June 3-5 (Tuesday-Thursday) at the Revere Hotel Boston Common, right in the center of the city. More details: loom.ly/jlsz-W4

In the Boston-Cambridge area? Come and meet our team in person to discuss your project. We'd love to meet you!

June 3-5 (Tuesday-Thursday) at the Revere Hotel Boston Common, right in the center of the city.  
More details: loom.ly/jlsz-W4
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Breaking news! This study just published in Nature ( nature.com/articles/s4158… ) is the result of a successful collaboration between Helix Biostructures and Dr. John Tesmer’s research group at Purdue University!

Breaking news! 
This study just published in Nature ( nature.com/articles/s4158… ) is the result of a successful collaboration between Helix Biostructures and Dr. John Tesmer’s research group at Purdue University!
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In the Boston-Cambridge area? Tomorrow, just off Boston Commons (Revere Hotel) is the Structure-Based Drug Design Summit (SBDD: loom.ly/A8ejNgw) and the Helix team will be in town. Come and say hi at our booth and let's chat about your projects.

In the Boston-Cambridge area? 
Tomorrow, just off Boston Commons (Revere Hotel) is the Structure-Based Drug Design Summit (SBDD: loom.ly/A8ejNgw) and the Helix team will be in town. Come and say hi at our booth and let's chat about your projects.
Helix BioStructures (@hlxbio) 's Twitter Profile Photo

Helix has arrived in Boston - we have a LIMITED number of adorable protein-shaped stress-balls to distribute to lucky passerbys. This is not a drill! (Also let's chat about your Structure Based Drug Design projects: loom.ly/A8ejNgw)

Helix has arrived in Boston - we have a LIMITED number of adorable protein-shaped stress-balls to distribute to lucky passerbys. This is not a drill! 
(Also let's chat about your Structure Based Drug Design projects: loom.ly/A8ejNgw)
Helix BioStructures (@hlxbio) 's Twitter Profile Photo

Today we’re at the 2nd Annual Structure-Based Drug Design Summit (June 3-5) in Boston, and proud to be here as an Exhibition Partner ( structure-based-drug-design-summit.com ). We’re especially excited about this year’s theme: “Harnessing Integrative Structural Biology Techniques"

Today we’re at the 2nd Annual Structure-Based Drug Design Summit (June 3-5) in Boston, and proud to be here as an Exhibition Partner ( structure-based-drug-design-summit.com ). We’re especially excited about this year’s theme: “Harnessing Integrative Structural Biology Techniques"
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Day 1 of the 2nd Annual SBDD (June 3–5) is off to a strong start! ( loom.ly/xFkoNIU ) Today’s sessions dive into key challenges in structure-based drug discovery!

Day 1 of the 2nd Annual SBDD (June 3–5) is off to a strong start! ( loom.ly/xFkoNIU ) Today’s sessions dive into key challenges in structure-based drug discovery!
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Today’s agenda delivered more great content, with sessions on time-resolved Cryo-EM, targeting flexible proteins, modulating protein–protein interactions, GPCR dynamics, next-generation vaccines, and more insightful discussions across the board.

Today’s agenda delivered more great content, with sessions on time-resolved Cryo-EM, targeting flexible proteins, modulating protein–protein interactions, GPCR dynamics, next-generation vaccines, and more insightful discussions across the board.
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Outstanding talk from our good friend Jeremy Setser, Senior Director of Structural Biology at Flare Therapeutics, showing how pocket remodeling around Y220A lets them capture an unreacted SNAr warhead and steer their covalent-inhibitor program. #SBDDBoston2025 #SBDD

Outstanding talk from our good friend Jeremy Setser, Senior Director of Structural Biology at Flare Therapeutics, showing how pocket remodeling around Y220A lets them capture an unreacted SNAr warhead and steer their covalent-inhibitor program.

#SBDDBoston2025 #SBDD
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Think of Helix as your structural biology problem-solvers: adaptable, experienced, and ready to dive deep. Meet Dr. Jungki Min, our Senior Scientist II, who brings serious depth to everything he works on: loom.ly/O_FdZYA

Think of Helix as your structural biology problem-solvers: adaptable, experienced, and ready to dive deep.

Meet Dr. Jungki Min, our Senior Scientist II, who brings serious depth to everything he works on: loom.ly/O_FdZYA
Helix BioStructures (@hlxbio) 's Twitter Profile Photo

Scientists LOVE working with Helix. Last month, Helix's X-Ray Crystallography work with Innoviva was published in the European Journal of Medicinal Chemistry: "Small molecule inhibitors of mannan-binding lectin-associated serine Proteases-2 and-3" loom.ly/UD2jwLM

Scientists LOVE working with Helix. 
Last month, Helix's X-Ray Crystallography work with Innoviva was published in the European Journal of Medicinal Chemistry: 

"Small molecule inhibitors of mannan-binding lectin-associated serine Proteases-2 and-3"
loom.ly/UD2jwLM
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A major advance just opened the door to high-resolution cryo-EM analysis of oxygen-sensitive proteins-this study presents a streamlined, blot-free vitrification workflow using the SPT Labtech chameleon to prepare cryo-EM grids under (an)aerobic conditions loom.ly/44PGyIY

A major advance just opened the door to high-resolution cryo-EM analysis of oxygen-sensitive proteins-this study presents a streamlined, blot-free vitrification workflow using the SPT Labtech chameleon to prepare cryo-EM grids under (an)aerobic conditions loom.ly/44PGyIY
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When you work with Helix, you partner with the best in the industry. Our featured employee is James Fuller, Director of Electron Microscopy. Learn more about his work in our latest team spotlight: loom.ly/pmUKgzQ

When you work with Helix, you partner with the best in the industry. Our featured employee is James Fuller, Director of Electron Microscopy. Learn more about his work in our latest team spotlight: loom.ly/pmUKgzQ
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Helix is proud to have supported this important research by performing the X-ray crystallography that helped advance the structural understanding of novel MASP-2 and MASP-3 inhibitors loom.ly/UD2jwLM

Helix is proud to have supported this important research by performing the X-ray crystallography that helped advance the structural understanding of novel MASP-2 and MASP-3 inhibitors loom.ly/UD2jwLM
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This Cryo-EM study offers new insights into how the molecular motor dynein is activated by its regulator: Lis1, a protein whose dysfunction is linked to neurodevelopmental disease loom.ly/QOspm9s

This Cryo-EM study offers new insights into how the molecular motor dynein is activated by its regulator: Lis1, a protein whose dysfunction is linked to neurodevelopmental disease loom.ly/QOspm9s
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A major step forward for cryo-electron microscopy AI applications: the release of CryoCRAB, a curated large-scale dataset created to support foundation model development in cryo-electron microscopy loom.ly/a9_bsLA

A major step forward for cryo-electron microscopy AI applications: the release of CryoCRAB, a curated large-scale dataset created to support foundation model development in cryo-electron microscopy loom.ly/a9_bsLA
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Helix's team is ready to help you and your department today. We are a group of passionate scientists who've experienced all the pain points and ins-and-outs of Cryo-EM, and are ready to set you up for success! Learn more about how Helix's team here: loom.ly/GfazN-o

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Exciting to highlight another Cryo-EM study advancing our understanding of GPCR biology. This work presents high-resolution structures of the histamine H4 receptor in complex with Gi, as well as the H1 receptor with noncanonical G proteins Gi and Gs nature.com/articles/s4200…

Exciting to highlight another Cryo-EM study advancing our understanding of GPCR biology. This work presents high-resolution structures of the histamine H4 receptor in complex with Gi, as well as the H1 receptor with noncanonical G proteins Gi and Gs nature.com/articles/s4200…
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This time next week, the Helix team will be at the American Crystallographic Association meeting in Chicago! #ACA2025 Will you be there too? loom.ly/BSot2Eo More upcoming events see here: loom.ly/v3gsg9U

This time next week, the Helix team will be at the American Crystallographic Association meeting in Chicago! #ACA2025
Will you be there too? loom.ly/BSot2Eo

More upcoming events see here: loom.ly/v3gsg9U