#️⃣3️⃣ [Developmental Biology]
In a groundbreaking study, researchers uncover MiniBAR's role in ciliogenesis, shedding light on cellular dynamics. Cilia, vital for signaling and development, pose a challenge in understanding their coordination. Led by Arnaud Echard, researchers…

📅 [SAVE THE DATE ] Don't miss the 3rd Edition of the Bio&Chem Forum.
It’s a unique opportunity to bring together researchers, industry partners, and students to foster dialogue and exchange ideas. Meet our colleague, Michael Mulot, on April 18-19, 2024 ! Learn more🔗…

Today 12h30 exciting research seminar at Rouen University on the nanobody pipeline for translational applications by Dr Jean-Christophe Rain, president of Hybrigenics SAS Hybrigenics Services, and partner of our ERA4Health_Partnership #HFpEF_DIVA consortium.

📅 [SAVE THE DATE]
Join us at the XXVIe Journées Francophones de Virologie! Thrilled to announce Michael Mulot and Jean-Christophe Rain participation in the 2024 edition. Hosted by Societe Francaise De Virologie in Brussels 🦠
With 500+ attendees, covering diverse virology topics. Don't miss this…

Thank you for your confidence in Hybrigenics Services and our ULTImate #Y2H technology platform !

Following an abnormally extended mitosis, cells activate p53 via 53BP1. Surprisingly, 53BP1 kinetochore localization is dispensable for this process. PLK1 activity, a negative regulator of 53BP1 localization, appears to be essential instead. embopress.org/doi/full/10.15…

📅 [SAVE THE DATE]
Come and meet our colleague Susan BENJAMIN at the C. elegans annual conference Ver Midi XXV on April 3rd ! Unravel protein interactions with our #PPI #Y2H based platforms and discuss the detection or blocking of your target using our #nanobodies .

🔬[ NEW PUBLICATION ]
Dig into the world of intracellular Hybrigenics VHH optimization with structural and functional information ! Some surprises along the way with the affinity levels achieved. Congratulations to Luc BUEE, I. Landrieu & Jean-Christophe Rain for their work ! 👏…

📅[SAVE THE DATE]
Come and meet our colleague Imenne Boubakour at AdTherapiesCongress to discuss about your cell and gene therapy projects for specific targeting or better targets’ characterizations with our #nanobody and #PPI #Y2H based platforms. We look forward to meeting you!

Meet with our colleague Brent Passer at the 2nd Molecular Glue Drug Discovery and Development Summit in Boston to discuss about your #TargetedProteinDegradation projects and our technology platforms. With our 25 years’ experience in #PPI screening and characterization and…

Last paper from 2023 highlighting #Y2H results from our platform is for the #HostPathogenInteractions topic in Journal of Biological Chemistry. Congratulations to Dr M. Boulanger from Dept. of Biochemistry & Microbiology at UVic, Jon Boyle et coll. A Yeast-two hybrid screen used T. gondii MAF1b as bait against our human fibroblast…

We are happy to share some of our 2023’s accomplishments. Results from our services were highlighted in 28 new papers for a total of 626 #publications . We enriched our catalog with 7 new libraries, and have now 140 #Y2H non-exclusive #libraries . We are also proud to contribute to…

Meet us at #CellBio2023 in Boston! Our scientific director Petra Tafelmeyer will present our #Y2H #ProteinInteraction and single domain antibody #VHH capabilities. Swing by our Booth#730 or our poster#B390 on Tuesday Dec 5, 2023 12:15 PM - 3:15 PM to discuss the right strategy…

Elegant regulation of #immunity in #CElegans ! Using our #Y2H technology platform to discover new interaction partners of PALS-25 and its mutant, the authors Emily Troemel were able to better characterize the “ON/OFF” immune switch regulating resistance against intestinal and…

We are ready for THE Protein& #Antibody Summit of the year #PEGSEurope ! Meet our colleague Abarna Lingeswaran to talk about #animal -free #Nanobody Selection, #VHH for intracellular applications and #YeastDisplay Optimization or swing by her poster A057: Phage and Yeast United for…

In order to identify novel telomeric binding proteins in #CElegans , the lab of Hiroki Shibuya Uni of Gothenburg employed our #Y2H technology platform and we identified new interactors DTN-1 and DTN-2 as direct partners. They act as negative regulators of telomere length and are…

#celegans GSC self-renewal maintaining worm fertility: with our #Y2H technology platform, the authors in Sivaram Mylavarapu lab @SivaramMV showed that the exocyst complex interacts via SEC-6 (EXOC3) with Par5 and Notch in both C. elegans and human cells. Learn more about our…

Mitofusin 2, as GTPase protein, orchestrates fusion of outer #mitochondria membranes and disruptions are causative for Charcot-Marie-Tooth disease. To gain further insights into the function of this crucial protein, we supported the lab of @ Brent Neumann with our #Y2H screening…

We invite you to attend, on October 9th, 11am, the IGBMC seminar:
“Phage and Yeast united for the better: Synthetic Nanobody selection and optimization”
by Dr Jean-Christophe Rain, CEO/CSO of Hybrigenics Services.
Please send your contact information to [email protected] to ease…