Gordon H. Guyatt
@GuyattGH
Promoting use of the best evidence and patient values and preferences to inform optimal clinical and health policy decisions. https://t.co/JxbX7cZMgy
10-06-2014 18:19:48
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Two articles highlight big problems when platform trials include non-contemporaneous controls. In addressing A vs no A, analysis should only use randomizations that included possibility of A. Should never use controls of B vs non-B.
nejm.org/doi/full/10.10…
sciencedirect.com/science/articl…