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Important study showing oral intake of pasteurized milk containing inactivated H5N1 does not induce oral tolerance against H5N1. Congrats @BriglebPam Ericka Kirkpatrick Roubidoux Stacey Schultz-Cherry !

US - "Utah Department of Agriculture and Food (UDAF) confirmed a diagnosis of highly pathogenic avian influenza (HPAI) in a commercial poultry flock." flutrackers.com/forum/forum/un… h/t Pathfinder #H5N1

Former Michelson Prize winner Dr. Jenna Guthmiller has been selected as the 2024 James S. Huston Antibody Science Talent Award Recipient. Congratulations Jenna Guthmiller! antibodysociety.org/uncategorized/…

EXCLUSIVE: My latest VANITY FAIR investigation examines why the federal response to the growing #H5N1 outbreak in dairy cows became marred by obfuscation + an unspoken `Don't test, don't tell' policy on America's farms, and how /1 vanityfair.com/news/story/ins…

Repeating to correct: Dept. of Agriculture reports a major jump in the number of #H5N1 #birdflu infected herds in California. Up 41 herds to 178. May be 30 more herds in the testing pipeline; top herd confirmed was CA 208. Latest Michigan herd (on my chart) still not confirmed by USDA.

Our study Cell defines an archaic allotype of the inhibitory KIR, KIR3DL1 observed in #FirstNations Oceanians with enhanced binding to HLA-A*24:02, important for NK cell immunity! #BrooksLab Katherine Kedzierska Rossjohn lab @PN0rmski cell.com/cell/fulltext/…

A potently #neutralizing and protective human #antibody with a unique antigenic footprint on #RSV and #hMPV fusion glycoproteins. Collaborative work with Jason McLellan Jarrod Mousa Rachel Bonami James Crowe Robert Carnahan, and others. biorxiv.org/content/10.110…

When your grant gets assigned to the study section you want it to go to.

I’m excited to see our paper posted medRxiv showing that older folks have higher levels of antibodies that recognize H5N1 viruses compared to younger individuals. Finally some good news for old people. 1/12 medrxiv.org/content/10.110…

So finally we've got some serology results from dairy workers in Michigan & Colorado: 7% seropositive. Glad these data have triggered new recommendations for worker protections, but as I told JoNel Aleccia, this should have happened months ago. apnews.com/article/bird-f…

BREAKING: Canada reports first human case of H5 bird flu The patient, a teenager from B.C., has been hospitalized. The source of the infection is unclear

Out today in Immunity! We define how sialylation of IgG Fc domains regulates NF-κB-driven responses in the lungs. sciencedirect.com/science/articl… Stanford Medicine HHMI NIAID CIVICs

.Dept. of Agriculture confirmed 62 new #H5N1 #birdflu infected dairy herds in California today, bringing CA's total to just under 400 & the cumulative national total to 612. That's 104 new herds in CA this week alone. Roughly 36% of the state's herds have now been infected.

Journals have an uncanny ability to send paper proofs the day before a long holiday weekend 🫠

Published article now available open access! nature.com/articles/s4146… Updates from pre-print: 1. High resolution cryo-EM structure of H5 with a receptor analog and the broadly neutralizing antibody CR9114 (PDB: 9DWE) 2. Updated analyses showing the role of T199I on RBS flexibility

Now over on Bluesky! Jenna Guthmiller.bsky.social

🌟 #ESWI 🏆 are open for #EarlyCareerScientists! 🌟 ✨ Young Scientist Vaccine Innovation Award 📅 Deadline: 28 February 2025 ℹ️ Eligibility eswiconference.org/eswi-awards#pa… 📽️ Hear from Jenna Guthmiller our inspiring 2023 winner. Will you be next? Showcase your innovation!

We have a new preprint on the receptor specificity of 2.3.4.4 H5 viruses out. We introduced the hallmark Q226L mutation in several antigenic backgrounds and observed different phenotypes. biorxiv.org/content/10.110… #H5N1 #glycotime

Want to read up on H5N1? A brief review out now from my group on where H5N1 came from, how it has or could evolve to better infect humans, and how the distribution of receptors for H5N1 can lead to varying symptoms, such as conjunctivitis. journals.plos.org/plospathogens/…

Congratulations to Dr. Omar Abudayyeh, Dr. Caleb Lareau, & Dr. Yuzhong Liu – the 2024 #MichelsonPrizes recipients! Learn more about their award-winning research here: humanimmunomeproject.org/news/human-imm…