Waiting for antimicrobial susceptibility tests is as nail-biting as it gets in the clinic—every hour lost results in the death of countless lives. But a new test from Seoul National University and QuantaMatrix slashes testing time by around 85%! insideprecisionmedicine.com/topics/precisi… via Inside Precision Medicine

There may be new hope in the hunt for reliable ways to detect cancer early on, an area where traditional dx methods prove inadequate. By analyzing cfDNA end-motifs, AI can distinguish patients with cancer. npj Journals insideprecisionmedicine.com/topics/informa… via Inside Precision Medicine

I didn't believe that AI-powered slide analysis could beat NGS to ID genomic biomarkers. But if it works, it could make precision oncology accessible and equitable. I spoke w/ UCSD Health Moores Cancer Center COE spinoff io9 about their Journal of Clinical Oncology study. insideprecisionmedicine.com/topics/oncolog… via Inside Precision Medicine

Congrats to Adaptimmune on their landmark U.S. FDA accelerated approval for their engineered T cell therapy for solid tumors, afamitresgene autoleucel (afami-cel)! insideprecisionmedicine.com/topics/patient… via Inside Precision Medicine

This is an ongoing thread for my series, "30 Essays to Make You Love Biology." ❤️🧬 I'll pin it on my profile.

8August: Why does Recursion reason it will benefit from its planned acquisition of Exscientia, announced today? Read details on the deal in my latest for Genetic Engineering & Biotechnology News: genengnews.com/topics/artific…

Is T1 diabetes really still treated with regular insulin shots? Aren't there other options, like transplants? I dove into this topic, covering the latest developments from UChicago Medicine, Vertex Pharmaceuticals, Garvan Institute of Medical Research, Eledon Pharmaceuticals, Inc., & more. insideprecisionmedicine.com/topics/precisi… Inside Precision Medicine

IPM's August issue is now live!! In it we the discuss the intersection of climate change and infectious diseases, taking precision medicine into the Cloud, new therapeutic uses for existing drugs, immunogenomics, and more! Read now for free:hubs.li/Q02LjP2G0

Touring TriLink BioTech's new GMP manufacturing facility for nucleic acid reagents to address modern health security threats (like pandemics) w/ BARDA brass was beyond impressive and only slightly intimidating. insideprecisionmedicine.com/topics/coronav… via Inside Precision Medicine

TIL even in transplant donors and recipients matched for HLA genes, the AA of the in minor histocompatibility antigens can cause rejection! Whole-exome seq (+scRNAseq) can personalize allo-HCT. Dana-Farber News Broad Institute Harvard Medical School insideprecisionmedicine.com/topics/precisi… via Inside Precision Medicine

Mary Lou Jepsen (Mary Lou Jepsen, PhD) takes the cake for the years most overstimulating and fast-paced interview—and it was awesome. Her new venture Openwater is blowing investors minds by open-sourcing their IP for inexpensive medical devices 👏insideprecisionmedicine.com/topics/precisi… via Inside Precision Medicine

My favourite discovery ever has just come online. Can I please tell you about some seriously wacky molecular biology? The story starts with a reverse transcriptase that SOMEHOW defends bacteria from viruses. (👇 I recommend sound ON for the video 🎹) 1/

There has long been an obsession with the ability to take a pill for any ailment or illness, and Biora Therapeutics wants to be able to do that. But can they? Check out my latest story for Inside Precision Medicine insideprecisionmedicine.com/topics/precisi…

There's a shortage of movement disorder specialists, making it harder for Parkinson's patients to see doctors. RuneLabsCEO Brian Pepin is changing that w/ an app that tracks data & makes AI-generated, HIPAA-compliant monthly reports. insideprecisionmedicine.com/topics/patient… via Inside Precision Medicine

Tomas Babak is a risk-averse drug developer. That's why he developed a clinically optimized driver-associated pharmacogenomics platform for shelved phase 2 drugs to hit solid tumor markets quickly & at a discount and launched Leapfrog Bio. insideprecisionmedicine.com/topics/oncolog… via Inside Precision Medicine

Superluminal Medicines, a concept in early 2022, now has 6 programs on small molecules for GPCRs, attracting $120M from NVIDIA's VC, Eli Lilly and Company, Catalio Capital Management, Insight Partners, Cooley LLP, & more. CEO Cony D'Cruz lays it out for me at Inside Precision Medicine insideprecisionmedicine.com/topics/informa…

The total # of drug-like compounds in small molecule catalogs is ~1/4 billion, but @Verseon CEO Adityo Prakash thinks the limit for possible compounds using rules for organic synthesis is a decillion (1e33). Prakash explains to Inside Precision Medicine how to do it: insideprecisionmedicine.com/topics/informa…

The use of CAR-T cells in autoimmunity is in full bloom. I spoke with Cartesian Therapeutics CMO Miloš Miljković, who explained the pros of using mRNA to engineer autologous cell therapies for myasthenia gravis (RMAT, May) & pediatric disorders. insideprecisionmedicine.com/topics/precisi… via Inside Precision Medicine