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We are here! Check us out at the Balloon Glow. Learn more about genomics and its role in health and medicine. #balloonglow #StL #Genomics

Thank you to everyone who stopped by to see us today at the Great Forest Park Balloon Race! Special thanks to our wonderful colleagues at Washington University in St. Louis for joining us and capturing this amazing photo of the balloons in front of the new NRB building!

📢Post-Doc Opportunity! The McDonnell Genome Institute, WashU Medicine and the Living Earth Collaborative are partnering to advance genomics for biodiversity research! 🔗apply.interfolio.com/158669 🌍livingearthcollaborative.wustl.edu #Genomics #Biodiversity #Conservation #Research #PostDoc #OneHealth

Why is ongoing investment in technology development so crucial? Bob Fulton, Director of Technology Development at MGI, explains how advancing genomic technologies has been key to answering critical research and clinical questions. youtu.be/apMfau23av0?si…

Excited to share our latest preprint, as part of ENCODE4, on a consensus variant-to-function (cV2F) score for functionally prioritizing variants for complex disease - led by Tabassum Fabiha and co-mentored with Alkes Price. biorxiv.org/content/10.110…

Six links to start your week. Machine learning, DNA design, chaperoneopathies, a genomic range extender, and a video tour of LLMs. open.substack.com/pub/thisgenomi…

Amazing new GWAS resource for CSF and brain metabolite levels (Metabolon, Inc.)🧠🧬 👉2,602 CSF samples of 440 metabolites 👉1,016 brain samples of 962 metabolites 📜Paper: nature.com/articles/s4158… 📊Summ stats: ebi.ac.uk/gwas/ [accession numbers GCST90317902–GCST90319303]

Biotech News: Wugen announces the company will initiate a Phase 2 trial for WU-CART-007 in the first quarter of 2025. wugen.com/wugen-to-initi…

Very cool paper showing the ability measure binding site occupancy on single chromatin fibers at targeted loci. This is going to be an important tool for assessing the effects of non-coding SNPs in single cells:

In pharma or biotech? Share your expertise by taking our survey. We are compiling a 2024 Multi-Omic Fee-for-Service Industry Report to highlight key trends, challenges, and innovations in the world of multi-omic services. washu.qualtrics.com/jfe/form/SV_0d…

Genomic deep learning when you don't have enough data for big models: x.com/genologos/stat…

Mayo Clinic's advancements in neuroscience highlight the field's ongoing evolution. At the MGI, we're aligned with this mission and leverage high-plex proteomics, genomics, and cell engineering to translate discovery into real-world impact for patients. newsnetwork.mayoclinic.org/discussion/8-i…

What technologies were needed to make the Human Genome Project work? Here are some of the 1980's origins of genomics and the McDonnell Genome Institute. If you like genomics and history, this is for you. open.substack.com/pub/thisgenomi…

Our Functional Imaging for Variant Elucidation (FIVE) technology hub presents SiDoLa-NS—a novel tool leveraging synthetic biophysical simulations to enable precise, multi-scale segmentation and atlas mapping for spatial omics in the nervous system. biorxiv.org/content/10.110…

Step inside the MGI—where genomics, high-plex proteomics, and mass spectrometry power discovery. See our team and cutting-edge tech in action, from sequencing to biomarker discovery. Watch the video: youtu.be/L7urIsC8YtY Illumina 10x Genomics PacBio SomaLogic Thermo Scientific

Delivering large DNA inserts into the mouse genome has been a persistent challenge. Here is Dr. Xiaoxia Cui, director of our Genome Engineering & Stem Cell center on a more efficient approach for CRISPR-based knock-ins: youtu.be/VwG0fPYqzcg?si…

The science behind a new non-opioid analgesic recently approved by the FDA: x.com/genologos/stat…

The New York Times profiled Lila Sciences, a company co-founded by one of our WashU Medicine Genetics Computational and Systems Biology graduates. Read more about Lila's AI-guided experiments:

With AI becoming an increasingly important discovery tool, every scientists should learn something about it. Here are some recommendations for learning about AI for everyone, ranging from easy math to grad level statistics. thisgenomiclife.org/p/how-to-teach…

Congratulations to WashU Medicine Professor of Genetics Susan Dutcher, who was elected to the US National Academy of Sciences this week. It is a well-deserved recognition of her outstanding scientific achievements.