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Very excited to share our latest work -demonstrating 50% diagnostic rate for CODE and 3 new CODE genes, MYO1A, GRWD1, and MON1A. NEJM The Genetic Architecture of Congenital Diarrhea and Enteropathy | New England Journal of Medicine nejm.org/doi/abs/10.105…

A 9 month-old baby boy with a fatal genetic disease was healed with the 1st-ever personalized n-of-1 gene-editing therapy. We live in an era of medical marvels.

Discover the #SyntheticBiology based innovations driving advances in human health and planetary sustainability! #SynBio26 🗓️11-13 March 2026 📎 bit.ly/3ZaYdwH Join us at the intersection of bioengineering and medical science for sharing, networking and collaboration.

🎉 Our new paper on live, intracellular #ClickChemistry just posted in Nature Communications! Huge shoutout to lead author Keqing Nian for all of the hard work 🙌🏼 Check it out 👉🏼 rdcu.be/enfHz

Optical Pooled Screening has transformed large-scale cell biology, but lacks robust end-to-end computational strategies to process these Tb-sized datasets. New from Di Bernardo et al (Matteo Di Bernardo): Brieflow. A game changer for OPS + new biological insights biorxiv.org/content/10.110…

The latest work from my lab, Phage Disco, a method Ellie Rand developed for targeted discovery of bacteriophages based on the bacterial receptor, defense system, or other component they interact with, is now live in mSystems

Stop the doom scrolling! A new 🗞️ from my lab, describing one of our flagship projects of many years we are super excited to share: "Inducible formation of fusion transcripts upregulates haploinsufficient CHD2 gene expression". A 🧵biorxiv.org/content/early/…

First student hooded from the Galloway Lab! Congrats, Dr Wang! Excelsior! Nat B. Wang 🧬🧑🏻‍🔬🏳️‍🌈 MIT ChemE Dept

Microglia feet are highly dynamic and can be in contact with dense networks of axons. In this video by our #ElectronMicroscopy team using MICrONS data, a microglia (purple) contacts with an excitatory pyramidal neuron (gold). Slowly the axons under the feet are revealed.

eradicating malaria doesn’t raise any ethical questions at all, actually

Oh wow, Eugenics just got a face-lift! Doesn't she look stunning! You can barely see the dark shadows of Mengele beneath her eyes

Lab is headed to MPS World Summit in Brussels to share our vascularized MPS models (liver & endometriosis). Preview of Priyatanu Roy's poster #394 "A microfluidic model of perfused vascularized hepatic tissue in a synthetic hydrogel matrix on the Physiomimix™ platform"

New from our lab: Jessica Shay Jessica E.S. Shay & Fangtao Chi Fangtao Chi show that high-fat ketogenic diets increase small intestinal tumorigenesis by enhancing fatty acid oxidation in stem cells, independent of ketone metabolism. In the colon, KD suppresses tumors—but also

'Transcription factor binding arrays as tools for mammalian engineering' led by the great Annalise Zouein is finally accepted Trends in Biotechnology! Co-lead with Tom Ellis, thanks to Katie Galloway and Brittany Lende-Dorn for working with us! Check this at: authors.elsevier.com/sd/article/S01…

Annalise Zouein's main PhD research paper is published today in Trends in Biotech. Trends in Biotechnology Building and using repeat transcription factor-binding arrays to modulate gene regulation in mammalian cells. No RNA, no protein - just DNA doing the work! sciencedirect.com/science/articl…

Engineering human pluripotent stem cell lines to evade xenogeneic transplantation barriers. Check out this resource by BIO5 Institute Deepta Bhattacharya & co-workers, published in StemCellReports #ISSCR2025 hubs.li/Q03rG31C0

The hearts started to beat in the pig–human hybrids, which survived for 21 days go.nature.com/4kEoRq7

This state is called "with editor"