The Kidney Contains Ontogenetically Distinct Dendritic Cell and Macrophage Subtypes throughout Development That Differ in Their Inflammatory Properties Barbara Schraml @gschotta Filippo Cernilogar bit.ly/30jo4CY

Ever wonder why children react differently to pathogens? Join our lab and help us find out! uni-muenchen.de/aktuelles/stel…

G4 quadruplex structures are cell type specific and associate with highly expressed genes. New preprint of a collaborative project led by Sara N. Richter biorxiv.org/cgi/content/sh…

HIV infection activates ERVs to regulate antiviral gene expression. Great collaboration headed by Daniel Sauter! academic.oup.com/nar/advance-ar…

Morc3 silences endogenous retroviruses by enabling Daxx-mediated H3.3 incorporation. Morc3 GHKL ATPase domain dimerizes for Daxx interaction. An efficient ATPase cycle is critical for H3.3 incorporation. biorxiv.org/cgi/content/sh…

G-quadruplexes are cell type-specific and associated with high transcription. Great collaboration with RichterLab Unipd Sara N. Richter

Here is our Snapshot of Human Endogenous Retroviruses (HERVs) that I wrote together with Johan Jakobsson for Cell (Cell). Enjoy reading here: authors.elsevier.com/a/1eS8aL7PXf0k2 - Helmholtz Munich | @HelmholtzMunich Lund Stem Cell Center

DNA sequence-dependent formation of heterochromatin nanodomains [Graeme Thorn, Christopher Clarkson, Anne Rademacher, Hulkar Mamayusupova, Gunnar Schotta, Karsten Rippe & Vladimir Teif] nature.com/articles/s4146… ChromHL software here: github.com/TeifLab/ChromHL Cartoon as a bonus!

H3K9me3 is not sufficient for silencing endogenous retroviruses if DNA methylation is perturbed. In Dnmt1 ko endoderm cells, IAP elements fully maintain H3K9me3, while trancriptionally active. great collaboration with Heiko Lickert out in Nature Communications rdcu.be/cVRqS

Setdb1 silences ERV derived cryptic enhancers to ensure proper hematopoiesis. Although transcription factors, such as PU.1, can bind to H3K9me3 heterochromatin, their activity is inhibited by Setdb1. out in PNAS: doi.org/10.1073/pnas.2…