Our theory of everything about the ecosystem of health decision-making: from fragmentation to synergy - enjoy the read in The Lancet Public Health aegis of World Health Organization (WHO) WHO/Europe with lorenzo moja Thomas Piggott MD PhD Elie Akl Carlos Cuello 🇺🇦 🇲🇽 🇨🇦 Pablo Alonso @ielluz ZuleikaSazP @RealYuanZhang Peter Tugwell ++

This is the central figure of how #primary studies #systematicreviews #HTA #essentialmedicines #evidenceinformedpolicy #qualityassurance #coveragedecisions are connected building on GRADE Working Group #EtD but there is more to come - available here: thelancet.com/journals/lanpu…

Background to the GRADE Working Group summary of findings tables for evidence about #values #outcomes #preferences #utilities @RealYuanZhang Pablo Alonso Hector Pardo-Hernandez Rebecca L. Morgan here: sciencedirect.com/science/articl… ☟

GIN Member conference - submit you abstracts by April 18 🗓 - we have a number of exciting sessions lining up in beautiful #Toronto - deadline for submission 🔜 g-i-n.net/conference_202… GRADE Working Group Cochrane JBI HTAi Health Canada and PHAC The Campbell Collaboration

Mark you calendars🗓: The next virtual GRADE meeting is on November 10 & 11 2022, details will follow - focus is now on the final preparations for the in-person meeting in Krakow Poland on July 12 and 13.

Already desperately needed: Updated framework of living guidelines: acpjournals.org/doi/epdf/10.73… Annals of Int Med World Health Organization (WHO) Elie Akl Joanne Khabsa Hector Pardo-Hernandez Arnav Agarwal +++ following GIN Member McMaster University checklist for #guidelines

The next critical piece to add to the puzzle 🧩 of getting our #guideline recs to help with self-directed health decisions. Of what value are “public health” recommendations if the PUBLIC doesn’t understand them? Rana Charide Tamara Lotfi (she/her) Grade centre Martin Offringa +++

GRADE stands with #Cochrane Cochrane Urology Cochrane US Network @CochraneUK Cochrane Centre Journal of Clinical Epidemiology Holger Schünemann @mwlangendam Philipp Dahm sciencedirect.com/science/articl…

Users must understand guideline recommendations-new rigorous trial shows the #RecMap enhances understanding & usability of World Health Organization (WHO) #tuberculosis guidelines journals.plos.org/globalpubliche… who.tuberculosis.recmap.org Tamara Lotfi (she/her) Thomas Piggott MD PhD Dominik Mertz Zain Chagla PLOS Global Public Health HEI

In preparation for a lecture on #evidencebased healthcare #ebhc I came across my old markings of the original Bradford Hill 9️⃣ viewpoints on causation. What a smart and world-changing paper that still is. If you haven’t read it, see what he said about statistical significance:

📢📢Join our team and make a difference! Your input can help shape guidelines for post-COVID-19 condition (long COVID). To learn more, visit: macgrade.mcmaster.ca/pccguidelines/ #LongCOVID #PostCOVIDGuidelines #Canada #CanadianHealthcare

#GRADESplit2023 Beth Radke from EPA assessing #riskofbias across studies, eg in #systematicreviews, in exposure studies ⁦GRADE Working Group⁩ - helpful to@understand the impact of confounding and other bias issues.

Next highlight: GRADE Adolopment guidance for approval Miloslav Klugar Elie Akl Shahnaz Sultan Holger Schünemann Gordon H. Guyatt Reem Mustafa Philipp Dahm

HEI's Thomas Piggott MD PhD and Holger Schünemann played a key role in the World Health Organization's landmark decision to add three #multiplesclerosis drugs to its Essential Medicines List. Read more here: rb.gy/my5me.

Here is our launch of the WHO/Europe manual for guideline adaptation based on GRADE Working Group adaptation methods. To be credible guidelines need to adhere to standards summarized in the book ⬇️ Zachary Munn Marge Reinap Elie Akl Miloslav Klugar GIN Member

PAHO/WHO Ludovic Reveiz on the evidence funnel in guideline implementation @who_euro #strengtheningcapacitytodevelopguidelines

@grade_wg members - please check our GRADE Teams channel for communication about our upcoming meeting on May 1 & 2, 2024. Those who want to become members or want to know more direct message us please. See many of you soon.

🚦Essentials for #evidencesynthesis #HTA #guidelines in The BMJ ROBVALU: a risk of bias tool for studies of people’s values, utilities or importance of health outcomes bmj.com/content/385/bm… Lawrence Mbuagbaw @hppardoh Pablo Alonso Adrienne Stevens Uwe Siebert Feng Xie

Will have important impact on overall rating of certainty for value, utility outcome importance studies!

Grade newsletter December 2024 is out linkedin.com/posts/grade-wo…