Toxic gain-of-function mutations in glycyl-tRNA synthase, underlying neurodegeneration in Charcot–Marie–Tooth disease, function by sequestering tRNAᴳˡʸ and causing ribosomes to pause at glycine codons. academic.oup.com/nar/advance-ar…

Correct link: genomebiology.biomedcentral.com/articles/10.11…

We are often asked, "what is the benefit of using multi-omics for #cancer patient stratification over panel #sequencing". answer: up to 5-fold improvement for #drug response #prediction. Limitations apply, details 👉 biorxiv.org/content/10.110… #MachineLearning #oncology #Genomics

📢📢 we received 970 applications for this year's computational #genomics focusing on #machineLearning applications. Thank you for the overwhelming interest, we will get back to the applicants in 7-10 days. MDC-BIMSB Max Delbrück Center

Artem from our lab presenting, for the first time, #gASOline , our tool for antisense oligonucleotide design leveraging RNA foundation models at #ncrna2024 in Basel.Artem Baranovskii Computational Health Center . Very grateful for all the biological insights on that!