#Meet_the_Frølund_Lab Welcome to our new MSc student Frederik Samuelsen, who just started in the group. He will be doing a 45 ECTS project focusing on both #computational and #organic chemistry for the GHB target 🖥🧪 In his free time, Frederik plays #handball 🤾🏼‍♂️likes #cooking

#meet_the_frølund_lab Our exchange MSc student from Milan University Gessica started in the group back in June2020 & soon finishing in Jan2021. She has been working on developing new flourescence probes for the #GABA receptors.

#Meet_The_Frølund_Lab Ida Aaberg Lillethorup is our MSc and #Lundbeck_Foundation scholarship student, who has been in the lab since Nov 2019. She is working on very exciting photocaging approachs with multiple future applications for both the #GABA & #GHB targets.

#Meet_The_Frølund_Lab Dr. Yue Xu (@yuexu4real ) just defended his PhD thesis after spending 3.5 years in the lab working on developing novel allosteric modulators for the #GABA targets. Now he leaves #Denmark and flys back to #China to start a new chapter of his life 👍🏻

10 years into the resurgence of covalent drugs | Future Medicinal Chemistry future-science.com/doi/10.4155/fm…

Targeting protein–protein interactions within GPCR and ion channel complexes provides an opportunity to develop more selective drugs with fewer side effects - find out more about advances towards realizing this goal in this review in the December issue go.nature.com/2K31D0H

Wishing you all a Merry Christmas 🎄 and a happy new year 🎉 Enjoy the holidays 🥳

#Meet_The_Frølund_Lab Jonas Odgaard Petersen is carrying a joint PhD project in the Clemensen, Strømgård, & Frølund labs bringing valuable skills in both peptide and small molecule design. He is trying to develop novel GLP-1 ligands to tackle pressing metabolic disorders e.g. #obesity

#Meet_The_Frølund_Lab Katrin Daraj is a pharmacist, who graduated with a BSc in Pharmacy from Damascus University in Syria. She is now doing her MSc degree in our lab where she is dedicating her ideas and efforts for the synthesis of novel ligands for the #GHB target.

Glad to highlight our new preprint identifying the allosteric binding site of the compound DS2 to the transmembrane region of delta-containing #GABA-A receptors. This was done using computational modelling and site-directed mutagenesis building on a wonderful

#Meet_The_Frølund_Lab Our Italian PhD student Ludovica joind the group after obtaining her MSc from Camerino university in 2019. At the moment, she is employing her talents and skills in MedChem for developing radiolabeled ligands to gain further insights on the #GHB target

#Meet_The_Frølund_Lab Our MSc student @lassebrokmose did his BSc in Chemistry at @Science_KU, before joining forces in our lab at @ILF last year. His prime focus now is to apply his fine skills & broad knowledge on developing novel binders for the #GHB target

#meet_the_frølund_lab After recieving a postdoc grant in 2019 from the Lundbeckfonden Mohamed Shehata (x_mo7med_shehata_x) joined the lab to employ computational chemistry methods and techniques to explore the #GHB target

#Meet_The_Frølund_Lab Nicoline Jensen is currently doing a 15ECTS study unit in #ComChem as part of her MSc in #MedChem in our lab. She is aiming at combining her modeling skills with her background in organic chemistry to find & optimize new chemical scaffolds for #GABA

Oops, fancy electrochemical reaction is going well in the Frølund lab!#electrochemistry #IKA #Chemistry #laboratory

DCF-SCI #NPCF13 #DCFSCI #CNS #INPCFMeet P7: A MedChem story on the development of novel selective α4β2 nAChRs partial agonists as smoking cessation aids. Find full JMC paper at pubs.acs.org/doi/10.1021/ac…

Happy to be part of this event that we dedicated to the memory of Prof. Maurizio Botta, founder/chairman of the workshop since 2006. Free with a great line-up of speakers: B. Botta Giovanni Appendino Wipf Group Frølund Lab D. Schinzer Dr. Donna Huryn & D. Liotta #EWDSy #drugsynthesis

DCF-SCI #NPCF13 #DCFSCI #CNS #INPCFMeet P60: Bioisosteric tools to improve the solubility of our lead MEDS 433

A very exciting story about identefying the long-sought brain taregt of Fantasy .. now out in #PNAS "GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain" Effort and work of Petrine Wellendorph Frølund Lab et al pnas.org/content/118/31…

#meet_the_frølund_lab Our creative & passionate Organic Chemistry senior year PhD student Yongsong TIAN (Yongsong TIAN ) is a very talented and dedicated chemist, both in the lab and for science in general. Yongsong works in the #GHB area, and loves adventerous exploration