We are part of UNION 🩷🌱 -Understanding mitochondrial lipid metabolism in ageing- We will offer 2 PhD position in our Madrid-based lab in 2025 as part of this exciting MSCA-DN. (+ 2 rotations in other outstanding European labs) JOIN US!!! @MSCActions #PhDPosition Please 🔁

Crosstalk between mitochondria–ER contact sites and the apoptotic machinery as a novel health meter: Trends in Cell Biology cell.com/trends/cell-bi…

A cell videoed through a microscope. The powerhouses/overlords of the cell, mitochondria, are shown in yellow. The nucleus is shown in cyan and actin filaments are shown in magenta. #CellBiology

Thrilled to share our latest work Puigserver Lab in Cell! Great collaboration with Vivek Sharma and #LiaoLab, where we show how the combination of #physiology, #cryoem, and #simulations can be implemented as a discovery tool.

Top Citations 2024: #19🏆✨ Laura Formentini (Centro de Biología Molecular Severo Ochoa) and co-authors describe how an ETFDH-driven metabolon supports #OXPHOS efficiency in skeletal #muscle via regulation of coenzyme Q homeostasis 🔄 nature.com/articles/s4225…

We have 2 PhD Positions🔥Join us in Madrid!!

Proximity proteomics reveals a mechanism of fatty acid transfer at lipid droplet-mitochondria- endoplasmic reticulum contact sites nature.com/articles/s4146…

📣 join us in Madrid!!! 3 years position 🐭

The wet, carbon-based matrix of biology behaves like an electrical circuit, slowly fluxing electrons from food ⊖ → ⊕ oxygen Through each step, energy flow meets energy resistance: éR éR is the fire of life, allowing transformation and adaptation Preprint here with the

Awesome. Great work, really impressive.

🔬 Talk by Laura Formentini (UAM, Spain): What makes our muscles efficient at using fats for energy? It turns out a newly discovered protein team—or metabolon—could hold the key. Here’s what we learned about CoQ, mitochondria, and metabolism. 🧵 #11thConferenceICQ10A

New Online! Key challenges and recommendations for defining organelle membrane contact sites bit.ly/4lnIBP1

Unlike what's in the textbook, neurons and the brain fuel on lipids... nature.com/articles/s4225…

Lipid synthesis supports membrane growth and organelle biogenesis. Sunyoung Hwang, Eduardo Torres et al. UMass Chan Medical School show that synthesis of sphingolipids, mainly long-chain bases, is essential to increasing nuclear membranes during #CellDivision. hubs.la/Q03vNnKP0

📌 Glucose Metabolism An amazing & versatile substrate! 🍒 🍑 #Biology #Metabolism #Nutrition #MedEd #Science

1/ 🚨 Our new paper is online in nature ! As its first author, I’m enthusiastic to finally share it with you all!🎉 🧠 We discovered a mechanistic link between cellular energy metabolism and the control of the need to sleep 💤 👉 nature.com/articles/s4158… Department of Physiology Anatomy & Genetics (DPAG) 🧵👇

.Claire Weckerly, Rahn, Gerry Hammond et al. University of Pittsburgh report a novel biosensor, PILS-Nir1, that detects phosphatidic acid in live cells, revealing the lipid’s dynamics with improved sensitivity and selectivity over existing probes. hubs.la/Q03HyBZn0 #lipids #phospholipids

New! Online now: The energy resistance principle dlvr.it/TNW23D

The Lipid Brain Atlas is out now! If you think lipids are boring and membranes are all the same, prepare to be surprised. Led by Luca Fusar Bassini with Gioele La Manno's lab, we mapped membrane lipids in the mouse brain at high resolution. biorxiv.org/cgi/content/sh…

New! Online now: The enedioic acid analog 326E alleviates metabolic dysfunction-associated steatohepatitis via dual targeting at ACLY and PPARα dlvr.it/TNqP3L