The Jagannathan Lab
@flyjagannathan
Exploring the biology of repetitive satellite DNA.
ID: 1100412309250494464
https://www.jagannathanlab.com/ 26-02-2019 15:08:33
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🎉🎉🎉🎉🎉 The first research paper from our group is out 🦟🦟🦟🦟 I am soooooooooo HAPPY 😍 nature.com/articles/s4158… IMB Mainz Felicia Basilicata Agata Kalita
Super excited to share together with Jocelyne Vreede and Peter Bolhuis my first research paper published in Nucleic Acids Research! We have developed a molecular simulation approach for predicting dissociation free energies of protein-DNA complexes:
Ever wonder why cells of the same type tend to have a pretty uniform size? Check out our new paper out in Molecular Cell today to find out why too big can be a bad thing in terms of genome homeostasis and proliferative potential. 🧵 (1/9) cell.com/molecular-cell…
Can cell growth become a competitive disadvantage? We think yes – In the first paper from our lab (🎉) super postdoc Sandhya Manohar finds that excessive cell growth destabilizes the genome - a collaboration with Federico Uliana and Robertus de Bruin authors.elsevier.com/sd/article/S10…
Are you curious about the proteins orchestrating nuclear architecture? Whether and how chromatin organization affects gene expression and cell fate? Check out our preprint showcasing recent work in collaboration with the Eric Joyce and @RanganLab. biorxiv.org/content/10.110…
Lastly, a big shout out to the all the collaborators especially the Eric Joyce, Randi Isenhart and Son C. Nguyen, @Ranganlab, Noor Kotb, Kutay Lab, Federico Uliana, and all the authors for their contributions. Huge thanks to The Jagannathan Lab for all the support and mentorship.
Do you use cell cycle arresting drugs in your research? Were you excited about recent papers on the relationship between cell size and senescence in Molecular Cell? If you answered yes to either of these, check out our review in The FEBS Journal! 🧵(1/5) febs.onlinelibrary.wiley.com/doi/full/10.11…
Sandhya Manohar Molecular Cell The FEBS Journal This beautiful figure created by Sandhya Manohar illustrates nicley how hyperactive cell growth might sensitize cancer cells to CDK inhibitors as suggested by the recent findings the Robertus de Bruin @Alexis_Barr Tony Ly Adrian Saurin labs and our group