You can read this article by Aleksandra Filipovska for free for the next 50 days at the following link: authors.elsevier.com/a/1jNoN3jDgWq3…

Check out our latest pre-print with Hauke Hillen and Ana Vučković, where we show that FASTKD5 joins RNase P and RNase Z in processing mitochondrial RNA. FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites biorxiv.org/content/10.110…

New paper from us on the in vivo role of the LRPPRC/SLIRP protein complex and its crucial role in mammalian mtDNA gene expression: academic.oup.com/nar/advance-ar… Congratulations Diana Rubalcava for great work! Thank you to all coauthors for a very nice collaboration.

🥳🚨Paper Alert🚨🥳 Excited to present our latest work on #Opa1 in this newly published paper Science Advances by sofia ahola and LilliAPazurek. We present here two new mouse models with impaired Opa1 processing. 1/🧵 science.org/doi/10.1126/sc… #mitochondria #mitochondrialdynamics MPI for Biology of Ageing

We are excited to announce the 12th ANZSCDB South Australia meeting taking place on October 16, 2024! Join us for insightful talks from McGlinn Lab, Cedric Bardy, and Dr. Lisa Marie Nicholas at Unisa. Don't miss this packed event! #devbio #science #cellbiology

Out today! We find that an epigenetic modification (6mA) to the mitochondrial genome (mtDNA) influences lifespan and the heritability of mtDNA mutations to the next generation. It implies that epigenetics determines genetic composition in future offspring. cell.com/cell-metabolis…

Our latest preprint! Some beautiful cell biology in this one. "Presynapses are mitophagy pit stops that prevent axon degeneration" biorxiv.org/cgi/content/sh… Discoveries into the cell biology of of mitophagy in axons, a disease mechanism, and a potential therapeutic avenue. 1/2

Better CRISPR base editors! More efficient nicking of the unedited DNA strand improves the ability to edit hard to reach bases. ACS Synthetic Bio pubs.acs.org/doi/10.1021/ac…

📢Registrations are now open for the ANZSCDB NSW Meeting! Scan the QR code to secure your ticket 🎟️👇

Mini reunion of team 'Mito Dysfunction' at Cell Symposia #CSMito2024! Wonderful to catch up with Aleks Aleksandra Filipovska from my PhD days in the Murphy Lab MurphyLab MRC MBU

Update! We outline AIVE, an AI method for volume EM data. We show the benefits of AIVE for reconstructing your FIB-SEM data, reveal some fascinating cell biology, and define intrusions as a new form of mitochondrial contact. biorxiv.org/content/10.110… Muscle mito nanotunnels 1/3🧵

New structural and functional analyses show that FASTKD4 supports non-canonical RNA processing and MT-ND3 mRNA stability. Thanks to all authors for their contributions and the reviewers for their kind advice! academic.oup.com/nar/article/do… #RNA #mitochondria #mtDNA

The peer-reviewed version of our paper on human tRNA 3' processing is now published in NatureStructMolBiol. Many thanks to the reviewers for their constructive comments! nature.com/articles/s4159… See also the very nice related work by Martin Hällberg Genis Valentin: embopress.org/doi/full/10.10…

Ready to make breakthroughs in gene editing and mitochondrial biology in sunny Western Australia? Join our vibrant team as a Research Associate or Research Fellow. Expertise in cryo-EM, cell imaging, or mammalian genetic screens is highly desirable staff.curtin.edu.au/explore-career…

📢 Hunter Meeting abstract submissions close 5pm AEST today! ANZSCDB is proud to have joined forces with the Hunter Meeting 2025. Please encourage your colleagues, postdocs and students to submit their abstracts today! Link: huntermeeting.org.au/abstract-submi…

Silencing mitochondrial gene expression in living cells | Science science.org/doi/10.1126/sc…. Wonderful that our paper is out now in Science. A big thanks to LD Cruz-Zaragoza and the team, Warscheid lab & JakobsLab .

It takes two to TANGO2! TANGO2 binds the heat shock protein crystallin alpha B to prevent aggregation of the intermediate filament desmin and its loss models TANGO2-deficiency disorder Many thanks to our team, collaborators and reviewers. rdcu.be/epI3p #metabolism

Dysfunctional mitochondria trap proteins in the intermembrane space | The EMBO Journal embopress.org/doi/full/10.10…

This poster is a must have for labs working on #MCS! A guide through the work of so many outstanding labs (apologies if we did not cite your work). Hang it in your office or lab, it will please your eyes and inspire your mind! Kudos to the driving force Antigoni Diokmetzidou! -LS

Our story about FASTKD5 is now published at Nucleic Acids Res. It was an amazing collaboration with Hauke Hillen and Antonio Barrientos labs. doi.org/10.1093/nar/gk… FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites