Can computations help drug discovery? Check out this review by Matteo Castelli and The Colombo Lab, which discusses new perspectives in cancer drug development Article 🔗 rsc.li/3ypruUS

Nascono qui, studiano con i nostri figli, condividono la cultura italiana: perché non possono essere cittadini? La legge sulla cittadinanza del '92 è anacronistica. La società è cambiata. Il Parlamento ne tenga conto. È tempo di approvare #iussoli e rafforzare la democrazia.

Very happy! 🥳Our paper on the discovery of pneumococcal serotype 19 common synthetic epitopes is out! #glycotime INNOGLY COST Action Very proud for this great collaboration! Thanks to Fabrizio Chiodo Instituto Finlay de Vacunas LUMC Leiden @lamorelli83 Luigi Lay pubs.acs.org/doi/10.1021/ac…

Happy to share this! How computational models can help understand the impact of mutations on antibody binding in #SARSCoV2 variants of concern. Thanks to @JCIM_ACS, alice, G4Lab_Pavia, Rasolab, Elisabetta Moroni, Università di Pavia pubs.acs.org/doi/10.1021/ac…

#MAUERvideo @MauerNft ZedJay Gabriella Majo75 alex d @everyone please, let's retweet, let's support this project. It really deserves to be discovered by more people!

Making better allosteric ligands by design? Yes we can! Here's our new work on the combination of computational design and experiments to discover novel chemical probes: tinyurl.com/zau4v5bb Rasolab Carlos Sanchez alice Luca Torielli Elisabetta Moroni Journal of Molecular Biology #CompChem

Fantastic collaboration with Prof Bernardes to unravel with unprecedented precision structure and immune properties of site selective glycoconjugates now published in Chemical Science @gbernardes_chem #glycovax pubs.rsc.org/en/content/art…

Beautiful!

Glycan-Based Conjugate Vaccine Candidate against Shigella pubs.acs.org/doi/10.1021/ac…

WORKSHOP “Neuroglycoproteins in Health and Disease” 24-25 March 2022 Alicante (Spain) innogly.eu/workshop-neuro… #glycotime

An overview on alternative/innovative methodologies for glycosidic bond formation in our latest review on CarbohydrateResearch Check it out! With @lamorelli83, Daniela Imperio and Luigi Panza. #glycotime INNOGLY COST Action Università degli Studi di Milano Biometra authors.elsevier.com/c/1fIoj1zTQmPr…

Find out how to discover and start drugging #protein interaction surfaces JCIM & JCTC Journals. Great work by PhD Student Luca Torielli. With Elisabetta Moroni and Lara Mussolin. Thanks Fondazione AIRC per la ricerca sul cancro Fondazione Città della Speranza Università di Pavia. #CompChem #drugdiscovery pubs.acs.org/doi/10.1021/ac…

On the importance of dissemination and communication is Science. Glycans and Glycosciences: an intro for everyone innogly.eu/glycans-and-gl… #glycotime

See how sequence evolution impacts the dynamics of #SARSCoV2 spike protein JCIM & JCTC Journals. Great work by PhD Student alice. With G4Lab_Pavia and Emanuele Casali. #CompChem #compbio pubs.acs.org/doi/10.1021/ac…

Can computation help understand biology? We discuss it in this paper. Elsevier Biomedchem Current Opinion/Research in Structural Biology Università di Pavia #compchem #machinelearning #drugdesign Structures, dynamics, complexes, and functions: From classic computati... sciencedirect.com/science/articl…

See how we combined structure, dynamics, a touch of #alphafold, and energy analysis to study the evolution of kinases ChemBioChem. Great work by Federica Guarra #compchem …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cb…

Our collaboration with Chiosis Lab N-Glycosylation-Induced Pathologic Protein Conformations as a Tool to Guide the Selection of Biologically Active Small Molecules, is published online in ChemEurJ: Chemistry - A European Journal Memorial Sloan Kettering Cancer Center Università di Pavia #computationalchemistry …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ch…

See our latest paper in Nature Communications, by Luca Torielli Federica Guarra Stefano Serapian Gestwicki Lab. We show how pathogenic mutations disrupt dynamics, rewire allosteric routes and impair function in chaperone Hsp60. #CompChem #MolecularBiology nature.com/articles/s4146…

Inhibition of sperm-egg interaction through a synthetic water soluble analogue of seminolipid. Towards the development of a non-hormonal contraceptive? Check it out! Università degli Studi di Milano Luigi Panza laura morelli #glycotime #glycochemistry #glycolipids mdpi.com/3281030

🚀New adventures in #DrugDiscovery: We designed multitarget leads that hit Hsp70, Hsp90 & Cdc37 at once—disrupting chaperone networks that fuel tumor growth. Collaboration with Mehdi Mollapour PhD, Gestwicki Lab Labs #CancerResearch #CompChem @AIRC Structure shorturl.at/gGk7m