Carles Fabregat-Franco (@fabregatfranco) 's Twitter Profile
Carles Fabregat-Franco

@fabregatfranco

Medical Oncologist, taking care of patients ✌🏽🩺 Interested in improving knowledge of hepatobiliopancreatic cancers 🔬🧬📚

ID: 1471534515407446022

calendar_today16-12-2021 17:35:52

90 Tweet

297 Followers

321 Following

Anirban Maitra (@aiims1742) 's Twitter Profile Photo

Incredible piece of work from Meritxell Rovira Jennifer Bailey-Lundberg and colleagues - this resource will be widely used. A functional map of the ENTIRE normal ductal epithelium from centroacinar cells to main duct, identifying both the transcriptomic heterogeneity to organoid forming

Incredible piece of work from <a href="/TxellRovira/">Meritxell Rovira</a> <a href="/DuctalvsAcinar/">Jennifer Bailey-Lundberg</a> and colleagues - this resource will be widely used. A functional map of the ENTIRE normal ductal epithelium from centroacinar cells to main duct, identifying both the transcriptomic heterogeneity to organoid forming
Charles Swanton (@charlesswanton) 's Twitter Profile Photo

What is the role of the TME in lung cancer evolution? We are excited to share our new TRACERx paper “Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer” at #AACR24, out in Cancer Discovery today rb.gy/q484j9 Tweetorial👇

What is the role of the TME in lung cancer evolution? We are excited to share our new TRACERx paper “Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer” at #AACR24, out in <a href="/CD_AACR/">Cancer Discovery</a> today rb.gy/q484j9 Tweetorial👇
KenOliveLab (@kenolivelab) 's Twitter Profile Photo

Stunning interim clinical trial data from Revolution Medicines... PFS = 8.1 mo in 2nd line KRAS G12-mutant metastatic #PDAC. OS not yet reached, but already more than a year! Benchmark PFS for this group is 2-3.5 months, behnchmark OS is 6.1-6.9. 1/

Stunning interim clinical trial data from Revolution Medicines... PFS = 8.1 mo in 2nd line KRAS G12-mutant metastatic #PDAC. OS not yet reached, but already more than a year! Benchmark PFS for this group is 2-3.5 months, behnchmark OS is 6.1-6.9.  1/
Grupo Español de Tratamiento de Tumores Digestivos (@grupottd) 's Twitter Profile Photo

📍TTD-Registro Español de Tumores Digestivos #RETUD cohorte BTC correlación de PFS-OS: Estudio con la colaboración del grupo RETUD ➡️Correlación entre SLP y SG en pacientes con cáncer de la vía biliar avanzado que reciben tratamiento sistémico antitumoral 🧵(1/2) #ESMOGI24

📍TTD-Registro Español de Tumores Digestivos #RETUD cohorte BTC correlación de PFS-OS: Estudio con la colaboración del grupo RETUD

➡️Correlación entre SLP y SG en pacientes con cáncer de la vía biliar avanzado que reciben tratamiento sistémico antitumoral

🧵(1/2) #ESMOGI24
Meritxell Rovira (@txellrovira) 's Twitter Profile Photo

Finally out the printed version of our single cell atlas of the entire murine ductal tree gastrojournal.org/article/S0016-… Followed by a really nice editorial from Rohit Chandwani gastrojournal.org/article/S0016-… Thanks to all the collaborators Jennifer Bailey-Lundberg lorenzopasquali Miltenyi Biotec

Finally out the printed version of our single cell atlas of the entire murine ductal tree gastrojournal.org/article/S0016-…
Followed by a really nice editorial from Rohit Chandwani
gastrojournal.org/article/S0016-…
Thanks to all the collaborators <a href="/DuctalvsAcinar/">Jennifer Bailey-Lundberg</a> <a href="/lorenzpasquali/">lorenzopasquali</a> <a href="/miltenyibiotec/">Miltenyi Biotec</a>
Arndt Vogel (@arndtvogel) 's Twitter Profile Photo

Clinical Value of Liquid Biopsy in FGFR2+ CCA During Targeted Therapy Clinical Cancer Research doi.org/10.1158/1078-0… 👉90% of FGFR2 fusion are detectable by ctDNA 👉⬆️level correlate w/ worse outcome & impaired liver function 👉good correlation w/ response & PD 👉Polyclonal resistence w/

Clinical Value of Liquid Biopsy in FGFR2+ CCA During Targeted Therapy
<a href="/CCR_AACR/">Clinical Cancer Research</a> 
doi.org/10.1158/1078-0…
👉90% of FGFR2 fusion are detectable by ctDNA
👉⬆️level correlate w/ worse outcome &amp; impaired liver function
👉good correlation w/ response &amp; PD
👉Polyclonal resistence w/
TIAN TIAN (@vicenttianfr) 's Twitter Profile Photo

We’re looking for a passionate PhD fellow to join our #VHIO team in cutting-edge #TranslationalResearch on #biliarytractcancer. Fully funded #FPI fellowship available! visit vhio.net/vhio-phd-oppor… #PhD #ScienceJobs #Oncology #cholangiocarcinoma

Journal of Hepatology (@jhepatology) 's Twitter Profile Photo

Immunotherapy for hepatocellular carcinoma ➡️The next evolution in expanding access to liver transplantation Read it here👉journal-of-hepatology.eu/article/S0168-… Michael Li, MD, MPH #LiverTwitter

Immunotherapy for hepatocellular carcinoma

➡️The next evolution in expanding access to liver transplantation

Read it here👉journal-of-hepatology.eu/article/S0168-…

<a href="/MichaelLiMD/">Michael Li, MD, MPH</a>
#LiverTwitter
Jia (Jenny) Liu MD PhD (@jiajennyliu) 's Twitter Profile Photo

KRAS inhibitors are a game changer esp in pancreatic cancer. Exciting tolerability and efficacy of KRAS(on) inhibitor RMC-6236 presented by David S. Hong MD #ENAsymp24. Registrational PIII trial open: clinicaltrials.gov/study/NCT06625…. Our internal waitlists for these studies ⬆️.

KRAS inhibitors are a game changer esp in pancreatic cancer. Exciting tolerability and efficacy of KRAS(on) inhibitor RMC-6236 presented by <a href="/DavidHongMD/">David S. Hong MD</a> #ENAsymp24. Registrational PIII trial open: clinicaltrials.gov/study/NCT06625…. 
Our internal waitlists for these studies ⬆️.
NEJM (@nejm) 's Twitter Profile Photo

In a phase 2 trial, researchers examined the safety and efficacy of the monoclonal antibody ponsegromab for treating cancer cachexia. Full trial results and Plain Language Summary: nej.md/3XE645a

In a phase 2 trial, researchers examined the safety and efficacy of the monoclonal antibody ponsegromab for treating cancer cachexia. Full trial results and Plain Language Summary: nej.md/3XE645a
OncLive.com (@onclive) 's Twitter Profile Photo

Alison Schram, MD, details data from the eNRGy study that supported the FDA approval of zenocutuzumab in NRG1 fusion–positive NSCLC and pancreatic adenocarcinoma. Memorial Sloan Kettering Cancer Center #lcsm #pancsm #oncology #MedTwitter hubs.li/Q034Ys8g0

Oncobites.tv (@oncobitestv) 's Twitter Profile Photo

📢 Día Mundial del Cáncer: 8 expertos analizan una década de avances en oncología 🩺✨ En OncoBites, reunimos a ocho líderes de opinión en oncología de España para conocer su visión sobre la evolución del diagnóstico y tratamiento del cáncer en los últimos 10 años. 👨‍⚕️👩‍⚕️ Sus

📢 Día Mundial del Cáncer: 8 expertos analizan una década de avances en oncología 🩺✨

En <a href="/OncoBites/">OncoBites</a>, reunimos a ocho líderes de opinión en oncología de España para conocer su visión sobre la evolución del diagnóstico y tratamiento del cáncer en los últimos 10 años.

👨‍⚕️👩‍⚕️ Sus
Brandon Luu, MD (@brandonluumd) 's Twitter Profile Photo

Lifestyle is a stronger predictor of aging and mortality than genetics. A new Nature study of ~500,000 people found: 🎯 17% of mortality variation was linked to lifestyle (exposome). 🧬 <2% of was explained by genetics. Here’s what you need to know 👇🧵 1/10

Lifestyle is a stronger predictor of aging and mortality than genetics.

A new Nature study of ~500,000 people found:
🎯 17% of mortality variation was linked to lifestyle (exposome).
🧬 &lt;2% of was explained by genetics.

Here’s what you need to know 👇🧵 1/10
Journal of Hepatology (@jhepatology) 's Twitter Profile Photo

📌In our March issue Intention-to-treat outcomes of patients with hepatocellular carcinoma receiving immunotherapy before liver transplant: The multicenter VITALITY study Read it here👉journal-of-hepatology.eu/article/S0168-… #LiverTwitter

📌In our March issue

Intention-to-treat outcomes of patients with hepatocellular carcinoma receiving immunotherapy before liver transplant: The multicenter VITALITY study

Read it here👉journal-of-hepatology.eu/article/S0168-…

#LiverTwitter
Pilar Navarro Lab (@pnavarro_lab) 's Twitter Profile Photo

🚨 We'are thrilled to share our last study in colab with Gabriel Rabinovich, Juan L. Iovanna & Martin Fernandez-Zapico Lab that reveals a nuclear role for Galectin-1 (Gal1) in pancreatic stellate cells (PSCs), directly regulating KRAS expression and reshaping the PDAC stroma. A thread! 🧵👇 PNASNews #PDAC

🚨 We'are thrilled to share our last study in colab with  <a href="/gabyrabi/">Gabriel Rabinovich</a>, Juan L. Iovanna &amp; <a href="/MFZlab/">Martin Fernandez-Zapico Lab</a> that reveals a nuclear role for Galectin-1 (Gal1) in pancreatic stellate cells (PSCs), directly regulating KRAS expression and reshaping the PDAC stroma. A thread! 🧵👇
<a href="/PNASNews/">PNASNews</a> #PDAC
ESMO Open (@esmo_open) 's Twitter Profile Photo

Genomic profiling unlocks new treatment opportunities for ampullary carcinoma in ESMO Open. Retrospective analysis showing over 50% of cases with actionable alterations, some responding to personalized therapies. esmoopen.com/article/S2059-…

Genomic profiling unlocks new treatment opportunities for ampullary carcinoma in <a href="/ESMO_Open/">ESMO Open</a>. Retrospective analysis showing over 50% of cases with actionable alterations, some responding to personalized therapies. esmoopen.com/article/S2059-…