To learn more about the methodology and results, check out our full paper here: biorxiv.org/content/10.110… Big thanks to Olivier Pourquie for the opportunity to work in his welcoming and supportive lab with great resources, and to all the authors involved in this work.

🇮🇱 👉DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression #FSHD pathogenesis 💡Smchd1 regulates alternative splicing in mouse NSCs, embryonic fibroblasts & embryonic stem cells 📰ncbi.nlm.nih.gov/pmc/articles/P… Francoise Helmbacher AnnemiekeAartsma-Rus Stanford Neurology & Neurological Sciences

Suite à un problème technique, nous avons dû créer un nouveau compte pour le centre français des 3R France Centre 3R. Je vous invite à nous suivre ! Due to a technical problem, we have had to create a new account for the French 3Rs centre France Centre 3R. I invite you to follow us

Hey!!! Don't forget to register for the Motor Mastery Symposium in Cologne. Great speakers from Europe and the US are going to show their research in Motor Control. See you there. 😃 motormastery.splashthat.com

Our new paper is out, Glia | Neurobiology Journal | Wiley Online Library onlinelibrary.wiley.com/doi/full/10.10… # cancer neuroscience, neural influence on Cancer, @univamu CNRS Biologie NeuroMarseille - NeuroSchool CENTURI - Turing Centre for Living Systems

If you are passionate about developmental biology and have bioinformatic skills, join us in Paris to research the anterior-posterior patterning!

🇨🇦🇺🇸 👉SMCHD1 activates the expression of genes required for the expansion of human myoblasts 💡DUX4-independent role for SMCHD1 in myoblasts suggests that the pathology of FSHD2 may be a consequence of defective muscle regeneration 📑pubmed.ncbi.nlm.nih.gov/38994563/ #FSHD Francoise Helmbacher

I am excited to share that our paper “Macrophage depletion protects against cisplatin-induced ototoxicity and nephrotoxicity” is now online in Science Advances. science.org/doi/10.1126/sc…

Congrats 👏 to Camille Dumas & Colleagues from the Kelly lab at IBDM, for the beautiful work, exploring how retinoic acid signalling regulates development of branchiomeric neck muscles at the trunk/head interface (trapezius) doi.org/10.1242/dev.20…

Research| Boulgakoff et al. show that during #cardiac regeneration, ventricular trabeculae participate in the repair of the contractile #myocardium, resulting in excessive production of immature Purkinje fibres and altering ventricular conduction. 👉 rdcu.be/dSnsS

Excited to share our work on trapezius muscle development!

We are recruiting a post-doctoral fellow in Melbourne on Tissue engineering and Spatial transcriptomics. Join us! careers.pageuppeople.com/513/cw/en/job/…

We are hiring! One main focus is to expand our muscle expertise UF Myology Institute #myotwítter. Come join a vibrant, diverse & collegial community that values mentoring. FLORIDA is surrounded by nature and is close to beautiful beaches & major attractions. tinyurl.com/5bmun25s

Je recrute un / une Ingénieur / ingénieure d’étude en neurobiologie humaine et animale (H/F), poste financé par @univamu Pour avoir plus d'informations et postuler, c'est ici : emploi.cnrs.fr/Offres/CDD/UMR… !

I am very happy to share our article on the characterisation of the MCM/FLExDUX4 mice. We highlighted several changes that could be used as markers of therapeutic efficacy and developed a force test that reflects the movements made in everyday life. #FSHD doi.org/10.3390/ijms25…

🚨 Exciting opportunity! SFBD needs 5 new board members, including a Treasurer (French-speaking) and a lead for social media/website communication. PhDs, postdocs, and young scientists welcome to apply. Deadline: Nov 27 at [email protected] #DevelopmentalBiology #YoungScientists

Preprint Alert! We show that intramuscular fat acts as physical barrier that inhibits muscle regeneration. Could targeting FAT enhance muscle recovery in clinical settings? THX to Terence Ryan. #myotwítter UF_Pharmacology UF Medicine biorxiv.org/content/10.110…

🇪🇺🇫🇷👉SMCHD1 genetic variants in type 2 #FSHD & challenges in predicting pathogenicity & disease penetrance 💡The intriguing relationship between D4Z4 methylation, SMCHD1 variants w/ SMCHD1 protein structure-function in FSHD nature.com/articles/s4143… Myologie Francoise Helmbacher

We managed to get one last paper rdcu.be/d5gAe over the line before the new year🥂! We are pleased to share the first Nature Cell Biology paper from our lab functionally validating the role of a frequently occurring lung cancer driver, FAT1 in cancer evolution. 🧵1/13

We are delighted that our last paper published Developmental Cell has been selected as one of the major breakthrough of the year by Inserm !!! calameo.com/read/005154450… Many thanks Inserm Inserm Auvergne-Rhône-Alpes GIN Neuro Grenoble European Research Council (ERC) Université Grenoble Alpes Alain Chédotal