Nice work from David Teis! Ubx3-Dsc2 ubiquitin ligase complex locally thins Golgi membrane, ubiquitinates proteins with short TMDs for degradation.
The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi biorxiv.org/content/10.110…

Interesting paper showing that focal adhesions and non canonical adhesions can interconvert! nature.com/articles/s4146…

🚨🚨🚨Dear X scientific community, we are looking for a FACS expert at UNamur Morph-Im platform 😎 A position is available. 🗣️Please spread the word! Don’t hesitate to contact me for more details or check link below 👉👉👉

📢 We are recruiting!!! 📢
A 3 year postdoc position is available in my lab to work on a Breast Cancer Now funded project investigating integrin-dependent #ECMatrix trafficking.
Closing date: 12th March
Apply 👇
jobs.shef.ac.uk/sap/bc/webdynp…
RT and DM for more info
Molecular and Cellular Biology Sheffield Cancer Research

Tension-induced adhesion mode switching: the interplay between focal adhesions and clathrin-containing adhesion complexes biorxiv.org/cgi/content/sh… #biorxiv_cancer

Our group is opening a permanent position (yes, permanent !) for a research engineer dedicated to image analysis and data analysis INSTITUT PASTEUR . More thorough description can be found here 👇

research.pasteur.fr/en/job/image-a…

We would be thankfull if you could spread the word 🙏

New preprint from our lab, by Montse Llanses , Keqian Nan, Zhe Bao, Rachele Bacchetti, Shengnan Yuan and joe: internalisation of integrin-bound #ECMatrix modulates invasive carcinoma cell migration biorxiv.org/content/10.110… (1/6)

⏰WE ARE HIRING

3+y postdoctoral positions in the context of a major Fondazione AIRC per la ricerca sul cancro grant 🎉

we will pursue our studies on mitochondrial mechanotransduction in breast cancer metastasis, including new mouse models & new drugs in the pipeline

Please RT and DM if you are interested

Signaling induced by substrate topography! What a cool story!!
Cogratulations to Renard Henri-François and to all his team members!! science.org/doi/10.1126/sc…

🚨Postdoc position available🚨

3 year position on reconstitution of phosphoinositide conversion cascades. You will combine supported lipid bilayer and imaging approaches to address membrane identity changes

Check out the lab website and to get in touch!

jobs.ac.uk/job/DEQ093/res…

Sci Hub is a 'pirate' website with 88M research papers freely available.

Using it is not advisable. We should all try to make billion-dollar acdemic publishers richer.

Here's a thread on integrating Zotero with Sci Hub to get free articles.

PLEASE DON'T DO THIS 😉

So finally, after quite a while and a lot of work from everyone involved, our work on #CAFs -mediated tumor compression is out in Nature Communications ! Big thanks to all authors! Carlos Pérez-González Xavier Trepat Danijela Matic Vignjevic Enjoy the reading!
nature.com/articles/s4146…

Attention cell biologists and lipid lovers: Want to visualise phosphoinositides without hassle and adverse effects of overexpression?
· Multiplex stain for all 8 PIPs
· Super-resolution imaging of nanoscale organisation
· From 2D to whole tissue
(1/9)👇
biorxiv.org/content/10.110…

Wonderful story about curved adhesions!
Focal adhesions are not the sole and unique adhesive structures of the cells :)
And finally #NatureCellBiology published a cell biology paper!! Congratulations to Bianxiao Cui and to all the authors!

TFM got a new brother: CFM (Confinement Force Microscopy) allows you to confine cells, tissue and even embryos between two elastic hydrogel planes: t.ly/G0ok0. We can study key migration processes like durotaxis 👇, AND get the 3D traction forces at the same time 🤩

Ubiquitin-driven protein condensation promotes clathrin-mediated endocytosis biorxiv.org/content/10.110…

Did you know that the intracellular mechanical properties can serve to differentiate between cell types🤔? Our new preprint biorxiv.org/content/10.110… even suggests new control mechanisms that allow cells to tune their active internal mechanics. Cool new science to be discovered🤩