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🫀 Heart failure with preserved ejection fraction accounts for half of #heartfailure cases. Here, Luxán and colleagues suggest reduction in STAT3 drives #pericyte loss, a hallmark of #HFpEF: ➡️ doi.org/10.1002/1873-3… Guillermo Luxán, Leah Vanicek, Institute of CVR, CPI,

What a fascinating first day at @embo @febs Lecture Course "Physical Virology: across length scales"! 🧬🔮🧪 Our Reviews Editor Julia is delighted to learn more about #viruses - and talk about our journals! Thank you to organizers Marta Bally Umeå University, Pedro de Pablo

How did #RNA and #ribozymes evolve during the #OriginOfLife 🌍? Nghe proposes a 3-stage scenario 🧬 #evolution ➡️ doi.org/10.1002/1873-3…

Day 2 at the Advanced Course "Physical Virology: across length scales" 🌊🧬 Today's sessions: "Physical virology at the host cell scale" + "Advanced Methods for Virology" – full of insights and inspiration! 🤯💡@embo FEBS #PhysicalVirology #EMBO #FEBS #Virology #ScienceLife

Day 3 at "Physical Virology: across length scales", exploring virus-inspired materials and enlightened by the EMBO Women in Science Lecture 👩‍🔬✨ And for a new perspective: Kayaking! 🚣‍♀️🌊 #PhysicalVirology #EMBO #FEBS #WomenInSTEM #Virology EMBO FEBS

⚙️ Isn’t it “touching” when cells communicate via #mechanotransduction? 🤝 Sampietro et al. explore mechanosensation in #Bcells and #leukemia: ➡️ doi.org/10.1002/1873-3… #mechanobiology #immunology

Our Reviews Editor Julia Hansen was delighted to attend the excellent EMBO FEBS course "Physical Virology: across length scales"! Thanks for great talks, poster sessions and the beautiful venue! 🌊☀️ #physicalvirology #virology #ScienceLife

🫀 A #cardiomyopathy-associated mutation in αB-crystallin causes this #HeatShockProtein to form #amyloid fibrils and disrupts key protein interactions. New research by Yousefi and colleagues explores the mechanism and offers potential therapeutic targets: ➡️

🎉🏅We congratulate 🌟Mathilda Lennartz🌟 MPI-CBG Dresden, on winning the FEBS Letters prize for the best short talk at #EMBOcellPolartiy25 in Sant Feliu de Guìxols, Spain! 👏👏👏 Photo: Mathilda with the meeting organizers Francesca Bottanelli Photo credit: Yuji Mizotani EMBO Events

🏅The winner of the FEBS Letters #PosterPrize at the Junior Scientists #Microbiology Meeting of Marseille is 🥁....🌟Josiane Azizi 🌟! 🎉Congratulations, Josiane! 👏👏👏 #JSM3Congress JSM3

‍👁️ #Choroideremia, a rare X-linked retinal degeneration, is linked to Rab escort protein deficiency. Sasaki et al. reveal that Rep-deficient #photoreceptors die via swelling and rupture, not apoptosis as previously thought: ➡️ doi.org/10.1002/1873-3… #retinaldisease

🧪 Kwon and colleagues achieve intracellular #IgG delivery with preserved antigen affinity by grafting a single CDR1 loop from cell-penetrating 3D8. Could this method unlock new strategies for #AntibodyTherapies? ➡️ doi.org/10.1002/1873-3… #Biotech #Immunology

🫧 In acidic environments, butyrate and other short-chain #fattyacids can accumulate in cells, causing cytosolic acidification. Van den Bogaart and colleagues explore how this impacts immune responses and epigenetics in macrophages: ➡️ doi.org/10.1002/1873-3…

🧑‍🔬 New in the #ScientistsForum: New in the Scientists Forum: #ResearchFraud and problematic images are undermining the reliability of #SystematicReviews. Jenny P. Berrío and Otto Kalliokoski identified issues with one in five studies for a systematic review on

🖼️ On the cover of Issue 11: 🦠 Can understanding #bacteriophage holins pave the way for #antibiotic therapies targeting membrane integrity? Biswas and colleagues report domain-dependent lytic activity of phage Phi11 Gp52 holin in FEBS Letters: ➡️ doi.org/10.1002/1873-3…

Chelatase activity of magnesium dechelatase associated with chlorophyll degradation febs.onlinelibrary.wiley.com/doi/10.1002/18… FEBS Letters

How do #GPCRs traffic via the #ER and #Golgi to the #CellSurface—and what goes wrong in disease? ⚙️ Review by Assoumou et al: doi.org/10.1002/1873-3… Miriam Stoeber