We are recruiting for a new Assistant Professor in the McKay Orthopaedic Research Laboratory Penn Medicine! Apply here! apply.interfolio.com/146051 Please submit applications by October 7th for consideration.

🔬 Looking for validated anti-ECM antibodies? Check out our latest antibody list curated from the Human BioMolecular Atlas Program (HuBMAP) Human Reference Atlas #HRA Organ Mapping Antibody Panels #OMAP on the Matrisome Project Portal: sites.google.com/uic.edu/matris….

Bulk RNA-seq analysis revealed a unique ECM pattern in colorectal cancer tumors, with ECM abundance and composition significantly related to patient survival. bit.ly/3AuZipv

Scientists investigate a mild-alkalization strategy employing magnesium boride-alginate hydrogels to rejuvenate #senescent cells associated with age-related diseases, finding corroborative evidence in both in vitro and in vivo experiments conducted on rat intervertebral discs.

Dr. Cato T. Laurencin and a team of researchers have made a potential breakthrough in understanding how porcine hydrogels can be applied for muscle and tissue regeneration. today.uconn.edu/2024/08/porcin…

Check out our latest work on how the metabolic environment modulate the competitive fitness and clonal expansion of Pik3ca mutant epithelial cells. Hats off to the super talented Albert_Herms and Phil Jones's team at Wellcome Sanger Institute. Thread to follow soon nature.com/articles/s4158…

🌱 A Columbia University team, including first author Dr. Rafaela Muniz de Queiroz, report a molecular mechanism where Mdm2 requires Sprouty4 to regulate #FocalAdhesion formation and metastasis independent of p53. 📕 Give it a read! go.nature.com/4fRZbV6

Get pumped!💪 A recent paper in PNASNews by Drs. Christopher Madl, Helen Blau, and team demonstrate that the mechanical memory #MuscleStemCells develop is rapidly acquired and not easily reversed by a change in stiffness. bit.ly/3XnVHTj

There's a little wrinkle in this research.... 🥁 Scientists develop a tissue-scale in vitro epithelial bilayer folding model that incorporates an epithelium and ECM hydrogel, emulating various folding structures found in in vivo epithelial tissue. go.nature.com/3AwykOm

It is believed that exosomal miRNAs facilitate intercellular signaling, which is essential for the development of cancer. 😎 Learn about role of miRNAs and cancer-associated fibroblasts in the #TME in this new CDD press story. go.nature.com/4e1oIcz

Researchers from Frankfurt Cancer Institute report that genetic and pharmacological inhibition of SOD1 leads to sensitization to hypoxia-induced cell death 💀 and disruption of redox balance under conditions of the #glioma microenvironment. go.nature.com/3XoOnH2

🌟Are you passionate about cancer research and eager to make a significant impact in the cancer field? 🎓We offer a PhD position to study the immunological landscape of colorectal cancer and the role of the tumor microenvironment in metastasis. 👉🏻 irbbarcelona.org/en/careers/you…

🕶️ Check it out! An implantable bioelectronics was developed that enabled the synchronization of the three stages of #WoundHealing, offering accelerated and high-quality healing of large skin wounds. bit.ly/4e32tmE

Kudos to Liam Leahy, Ian Woods, and the whole research on team on this new release! ✨ 📖 Give it a read: bit.ly/478xPG8

Curious about 💕 heart valve #regeneration? Scientists formed a double network hydrogel on decellularized heart valves, showcasing robust anti-calcification and anti-thrombosis properties post fatigue testing. 🔗 go.nature.com/3AK20HP

So mesmerizing! #SciArt 🎆

Targeting the tumor vasculature: from vessel destruction to promotion. 🧐 CCB_VIB_KUL researchers alongside Dr. Sophie Guelfi from BergersLab provide an overview of #vascular targeting approaches. 🔗 go.nature.com/3ALwmtp

😎 Check it out! Dr. Alexandra Naba (Naba Lab @ UIC) discusses novel insights into the compositional diversity of matrisome components. Nature Reviews Molecular Cell Biology Give it a read: go.nature.com/4dTQd8E

Modulating #hyaluronan matrix functions by targeting its binding partners holds promise as a therapeutic strategy for restoring tissue homeostasis and mitigating pathological processes. Learn more in this Nature Reviews Nephrology review! 👇 go.nature.com/4ecmo2A

Hot off the press! 😍 Yueming Liu, Aidan Gilchrist, and Sarah Heilshorn discuss the modular design of engineered protein-based #hydrogels from both a molecular- and network-level perspective. Heilshorn Lab Find out more in 👉 Advanced Sci News | bit.ly/3z7HiRE