Evidence from omics that aging is not a gradual, linear process. The new study, highlighted here, only assessed people up to age 75 among 108 participants with short term follow-up (1.7 yrs). A previous large study (N>4,200, up to age 95) found a 3rd peak at age 80.

An important finding that may lead to new ways of preserving brain health in the future "Astrocytes acquire stem cell function through changes in DNA methylation" nature.com/articles/s4158… nature Martin-Villalba Lab Martin Villalba and colleagues justsaysinmice open-access

A wearable sensor band that uses microfluidics to analyze sweat pH and lactate during exercise, potentially a metric for promoting or quantifying level of physical fitness science.org/doi/10.1126/sc… Science Translational Medicine

We know atherosclerosis shows up early in life in some people, in late teens and 20s. Now the effect shown of early, intermittent exposure to high blood lipids in children, ages 6-12 yrs, with a mechanism involving macrophages as found in mice nature.com/articles/s4158… nature

What slows or speeds brain aging? This is just 1 of 10 recent papers in today's nature nature.com/articles/d4158… This one along with the others are reviewed in the new Ground Truths, link in my profile

I really appreciate Eric Topol inviting me on his terrific podcast, Ground Truths. If you listen you'll see he did his homework and reveals my 'not-so-secret' former career...

Just out Science Magazine The aged immune system promotes cancer progression, implicating interleukin-1 ⍺ as a key mediator, as seen in old mice model and patients, with potential path for therapy science.org/doi/10.1126/sc… Miriam Merad, MD, PhD Lipschultz Precision Immunology Institute Icahn School of Medicine at Mount Sinai

Snippet from full video youtube.com/watch?v=0iUMaa… on Joe's unique background!

A 5★ review of the vessel wall endothelium in health and disease, open-access Cell cell.com/cell/fulltext/… by Hellmut Augustin and Gou Young Koh (Gogh)

Largest prospective study of #LongCovid in children and teens with 3-year follow-up thelancet.com/journals/eclin… by La Campo - Anna Camporesi and colleagues —significant, long-lasting impact —increased risk of autoimmune diseases —reduction of risk with vaccination/boosters, especially among teens