Synple Chem (Synple Chem) and Enamine partner to jointly develop a new chemical space by fueling the world’s largest collection of building blocks provided by Enamine to Synple Chem’s reaction outcome prediction tools.

Read full Press Release: bit.ly/3JGtQ9c

We are excited to participate in the 19th BIO KOREA International Convention, which will be held on May 8-10, 2024, at COEX, Seoul.

Explore collaboration opportunities by scheduling a one-on-one session with us: enamine.net/contact

Event information: biokorea.org/index.asp

Molecule of the week EN300-6736286
More details: bit.ly/4d78OOi

#Enamine #molecule #chemistry #science #drugdiscovery

Congratulations to Pavel Mykhailiuk, DSc, on being awarded the Liebig Lecturer 2024 for his outstanding contributions to organic chemistry!

Further details on lecture series will be published on bit.ly/3UvOjUc

Cyanopyrrolidine has been used to develop the inhibitor of cysteine protease.
Enamine updating the Screening Library each year with the latest trends in covalent warheads.
Learn more about Enamine Covalent Screening Library enamine.net/compound-libra…

Enamine offers a plethora of rare and often unique γ-amino acid structures for modulating the conformation, molecular volume, polarity, reactivity, and more: bit.ly/3JmQR0v

Try our γ-amino acids in your research!

The CH₂ group of the acetamide moiety represents an attractive attachment point for additional exit vectors. Involving this carbon in the piperidine ring greatly increase the compound’s potency on LPAR1 and improv its metabolic stability.

EnamineStore:tinyurl.com/bddhcef5

Aromatic methyl sulfones are popular (>30 drugs). Heteroaromatic ones are not (lack of approaches). Not anymore!
A new reagent towards methyl sulfones in one step!
Today in ChemRxiv bit.ly/3W0nWqA

Molecule of the week EN300-7120494
More details: bit.ly/3vPKRuj

#Enamine #molecule #chemistry #science #drugdiscovery

Explore Bienta’s (Enamine Biology Services) automated assay based on a High Content Imaging (HCI) setup. You will benefit from bias-free, high-throughput analysis which requires no more than 2-3 mg of the compound of interest to be tested.

More details: bit.ly/3JkFDcZ

Inclusion of the oxabicyclo[2.1.1]hexane in the target molecule could help achieve excellent microsomal stability while maintaining picomolar potency and low efflux.
Try our oxabicyclo[2.1.1]hexane building blocks in your research! tinyurl.com/muasc5c7

Explore our Covalent Enantiomeric Pairs Library, featuring over 2k novel covalent modifiers synthesized from more than 6k chiral building blocks with high enantiomeric excess (ee) purity.

Available in 100 mM concentrations for fast supply.

More info: bit.ly/3VWCLe2

We are excited to participate in the 35th Symposium on Medicinal Chemistry in Eastern England in Stevenage, UK, on April 25.

Explore collaboration opportunities by scheduling a one-on-one session with us: enamine.net/contact

Event information: rscbmcs.org/events/mcee35/

Outstanding spirocyclic aminoalcohol by Enamine Ltd 🇺🇦 chemists! Check out similar compounds on the website!
#nmr #nmr chat #chemistry #organicchemistry #spectroscopy #drugdiscovery #drugdevelopment

Molecule of the week EN300-47314148
More details: bit.ly/3UgdvxK

#Enamine #molecule #chemistry #science #drugdiscovery

Metrion Biosciences (Metrion Biosciences) and Enamine are excited to announce a strategic enhancement to Metrion’s High Throughput Screening (HTS) services with the addition of access to Enamine’s compound libraries.

Learn more: bit.ly/44baTVD

Enamine team sends best wishes from the EFMC-ACSMEDI Medicinal Chemistry Frontiers 2024 Symposium!

Our chemists introduced difluorobicyclo[1.1.1]pentane as a structure that matches the exact molecular volume of the benzene ring while elevating sp³ character and solubility of the substance: bit.ly/49uVCzV

Try our difluorobicyclo[1.1.1]pentanes in your research!

Discover how AI revolutionizes drug discovery in the latest study: “AI is a viable alternative to high throughput screening: a 318-target study”, leveraging Enamine REAL library to identify novel molecules.

Read more: doi.org/10.1038/s41598…

Visit: enamine.net/compound-colle…

Molecule of the week EN300-28312057
More details: bit.ly/3J5YwQI

#Enamine #molecule #chemistry #science #drugdiscovery