A great study on the relationship between cancer cells, stroma and multifactorial drug resistance was presented by Andriy Marusyk from Moffitt Cancer Center. Moffitt Cancer Center #AACRevol23 #AACR

Congratulations to Ryan Schenck and Maureiq Ojwang for their talks at the AACR Special Conference in Boston! #AACREvol23 #AACR #cancerevolution

Next up is friend and Jake Scott lab member @MathEvoRowan presenting, Topology of the tumor microenvironment; integrating imaging, modeling, and topological data analysis #AACRevol23

Peter Laird From Van Andel Institute presents how global and local DNA methylation contributes to cancer development #AACREvol23 #AACR #CancerResearch

Laird: The slope of the hypomethylation with age was slightly different in different tissues, so the rate of hypomethylation per cell division may vary with organ biology/context #AACRevol23

.Valentina Boeva is talking next about "Unraveling potential genetic drivers of intratumor transcriptional heterogeneity and phenotypic plasticity in malignant cells" #AACRevol23

.Noemi Andor: ALFA-K is available on github - designed and implemented by Richard Beck #AACRevol23

Noemi Andor (Noemi Andor) has been presenting the last seminar so the headliner of the 2023 AACR Special Conference "Translating Cancer Evolution and Data Science: The Next Frontier" and informs the audience on ALFA-K. #AACR #AACREvol23 #CancerEvolution #Aeneuploidy

The final presentation of #AACREvol23 is from our very own Noemi Andor presenting new work on, Adaptive local fitness landscapes for aneuploid karotype IMO Moffitt Cancer Center

If you are a High School student aged 16 or older and interested in learning how you can apply mathematics to cancer then consider applying to the Mathoncoblog fully funded High School Internship summer program Moffitt Cancer Center: moffitt.org/education/rese…

Todays IMO research in progress is from Noemi Andor lab member Richard Beck presenting, Modelling the Evolutionary Landscape of Aneuploidy Moffitt Cancer Center

It will be a great pleasure to attend and present at the 1st Polyploid Giant Cancer Cell Conference at the MD Anderson Cancer Center in Houston this week. MD Anderson Cancer Center #Houston #Polyploidy #Cancer

Excited to announce that registration for the 12th IMO workshop on Treatment Toxicity is now open. Held onsite Moffitt Cancer Center Nov 3-Nov 8 #MoffittIMO more details: imo12.eventbrite.com. Deluxe travel awards are available on a competitive basis, apply by 09/30!

Exciting keynotes NIH #NCIITCR #ITCR2024 meeting, cover the lifecycle of emerging #tools from #Cancer #Research to #Cancer #Care! itcr2024.org National Cancer Institute @NCIDataSci #InnovationInHealthcare #HealthcareAI #FederatedLearning #CancerResearch #CancerCare #MachineLearning #AI

Excited to share our software CLONEID at the #ITCR2024. CLONEID collects and maps genotypic and phenotypic data, across space & time. Use cases demonstrated by Thomas Veith and Richard Beck . Thanks to the #NCIITCR National Cancer Institute for funding the work!

Compelling talk from Ben Raphael at the #ITCR2024 on quantification of spatial heterogeneity. Looking forward to using CalicoST to inform our mathematical models of chromosome mis segregations!

Today at #ITCR2024 we looked at CLONEID’s role in collecting genotypic and phenotypic data. Use case demo was a long term evolution experiment led by Vural Tagal with Jackson Cole

Excited to see this out! Huge credit to @Zuzannows and Frederika for leading the way. Our S3MB model recapitulates GBM growth and karyotype evolution post-surgery, revealing how resource access shapes tumor ploidy. Grateful to have been part of this with such a fantastic team!

Live from #AACR25: Alexander Anderson, PhD, (Sandy Anderson) leads the Adaptive Therapy from Board to Bench to Bedside and Back Again symposium. He shares how evolution-inspired treatment strategies like adaptive therapy can optimize drug use, delay resistance and improve outcomes