EFFECT Trial
@effecttrial
EFFECT Trial: Efficacy of Flucytosine & Fluconazole as Early Cryptococcal Treatment. Phase 3 RCT at 13 sites in South Africa, Tanzania, Vietnam. Funded @The_MRC
ID: 1489538211189772292
http://www.isrctn.com/ISRCTN30579828 04-02-2022 09:56:18
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IMPRINT Fungal HIV Global Research Grp investigators meeting at UCT. PIs Nelesh Govender and Joe Jarvis. Tackling fungal infections in PLHIV … improving implementation and advancing science
Fantastic to have experts from UCT Division of Public Health Medicine Health Economics Division collaborating in the IMPRINT Fungal HIV Global Research Grp group and assisting on our EFFECT Trial health economics substudy with UCL and LSTM
Many of our investigators are participating in #ICCC2023 in Kampala this week. Today, a master class in the clinical management of cryptococcal meningitis with David Lawrence @KylaComins and colleagues from SHARE-CM discussing implementation of the AMBITION Study regimen 💊💉
Our co-CI Nelesh Govender (also @neleshg.bsky.social) presenting on CrAg screening programmes, in which the EFFECT trial is embedded. Our other co-CI @Molloy_Sile presented EFFECT Trial earlier this morning during the #ICCC2023 Clinical Track CrAg Screening sessions. Working our way to #endcryptodeaths by 2030💉💊
Valuable insights from David Lawrence on patient perspectives of the AMBITION Study regimen. Bottom line: staff and patients prefer a single dose of L-Amb. "They want one yellow, not 7 yellows"💉🟡 Now to push for implementation with SHARE-CM and IMPRINT Fungal HIV Global Research Grp 🧫🦠🧠
St George’s researchers are leading an international trial which aims to improve treatment to prevent a type of meningitis that attacks the brain in people with advanced HIV, thanks to £4.5m funding from Medical Research Council. Learn more about the EFFECT Trial: sgul.ac.uk/news/4.5m-inte…
Is fluconazole enough for cryptococcal antigenaemia? The EFFECT Trial is exploring the impact of flucytosine plus fluconazole in South Africa and Tanzania. Thrilled to be part of this wonderful team!
Thrilled that today Joe Jarvis and I were able to represent the huge and wonderful AMBITION Study team and receive the EACS European Hector Research Award for best clinical/epidemiological paper in HIV in the last two years. Dedicated to all participants #EACS2023
Great week in S Africa Doctors Without Borders (MSF) Southern Africa discussing all things cryptococcosis, histoplasmosis & advanced HIV disease. Now Wits University where I gave a lecture on interdisciplinary research within IMPRINT Fungal HIV Global Research Grp & met Nelesh Govender (also @neleshg.bsky.social) & our EFFECT Trial social science team NIHR Global Health
We are thrilled to share that we are down to double digits! 99 participants left to reach out recruitment target of 600. Looking forward to contributing meaningful data to help to #EndCryptoDeaths 🦠🏥💯 Nelesh Govender (also @neleshg.bsky.social) Sile Molloy Joe Jarvis Kyla Murphy